Sounds like an interesting newsletter.
The recommendation to take higher amounts of folic acid is because: a) Crohn's patients have problems with absorption of vitamins and minerals, absorbing less than the average person and b) some medications, like sulfasalazine, interfere with folic absorption.
So while 400 might be OK for a healthy person, it might not be enough for a Crohn's patient. Blood tests can reveal whether serum folate is low or falling.
Folic acid deficiency can cause anemia, cognitive decline, and increases the risk of cancer according to the following article:
Post Edited (njmom) : 11/6/2007 12:29:32 AM (GMT-7)