So 4 months on 6mp (now on 100mg) and no help really. I have done 2 remicade treatments during that time also. Just did a few weeks of cortifoam. No real relief. Im so inflamed that even air is trapped. I cant hanlde the pressure. Anyway doc now wants to start flagyl and a probiotic. Please tell me what to expect and any suggestions you have to make it most tolerable. I am only gonna give the 6mp 2 more months to start working. Then, if no help, im going off it! I am so exhausted and fatigued ALL the time and i think the 6mp really contributes to that. Thank you guys.