Bad taste from prednisone. What do you do?

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Regular Member

Date Joined Jul 2005
Total Posts : 207
   Posted 11/24/2007 8:03 AM (GMT -6)   
Hey everyone..I just took my prednisone for the morning and I am sitting here with this awful taste in my mouth from it. I have tried taking a drink before takign it, not taking a drink, drinking it with milk but yuck that awful tatse is still there. even if it just sits in my mouth for 1 second. It shows how evil it is. Any suggestions on how to cut that bad bad flavor? The good news is I just got to tpaer to 50mg and next week to 40 mg so hurray !
28 Year old Female. Dx with Crohns 2005. Currently take Imuran 50 mg.
Dx with Pyoderma Gangrenos (PG) Nov '07, currently on Prednisone 60mg for PG ...  :(

Veteran Member

Date Joined Mar 2007
Total Posts : 4527
   Posted 11/24/2007 9:14 AM (GMT -6)   
Hi Glad you get to taper . I just take them with my breakfast half way threw and try to swallow them as fast as I can and then eat some more breakfast. Hate to say it but I guess I am getting used to it or something because it doesn't bother me as much they are nasty if you leave them in your mouth too long .Could try putting them furthur back in mouth but not too far . Good luck and happy tapering. lol gail

Veteran Member

Date Joined Sep 2007
Total Posts : 565
   Posted 11/24/2007 10:23 AM (GMT -6)   
i know, those pills are terrible! i usually eat apple sauce or canned fruit for breakfast and i do the same thing as gail. eat some breakfast, take pills, eat mor breakfast. and also, i have my little trick! i take a sip of juice, don't swallow it, tilt my head back, drop the pill in and then swallow. that way it doesn't hit my tongue :p
.: stephanie :.
32 y/o female diagnosed 8/8/7 with crohn's of the terminal ileum w/ stricture/scarring
15mgs prednisone (getting there!), 25mgs 6mp, 4000mg pentasa, vicodin for pain & boat load of other drugs for sleep and anxiety!

Regular Member

Date Joined Jul 2005
Total Posts : 207
   Posted 11/24/2007 10:46 AM (GMT -6)   
Thank you both.. I think i will try the juice idea and see about putting them further in my mouth..its just such a crummy way to start the morning ya know ?
28 Year old Female. Dx with Crohns 2005. Currently take Imuran 50 mg.
Dx with Pyoderma Gangrenos (PG) Nov '07, currently on Prednisone 60mg for PG ...  :(

Veteran Member

Date Joined Sep 2006
Total Posts : 2527
   Posted 11/24/2007 11:04 AM (GMT -6)   
I hate the taste myself but just live with it or brush my teeth and use mouthwash after. My exhusband's cousin when he was on it for bronchitis (he is a child) would chase the pred with a spoonful of mustard
Dx with Crohn's 1987, symptoms as early as 1984.
Temp iliostomy February 2007, reversed June 2007, Ovarian cysts, migraines, allergies (incl food allergies) , oral allergy syndrome (diff than true food allergies), Asthma, Gall Bladder removed 1999, Inguenal hernia 1987

Regular Member

Date Joined Oct 2006
Total Posts : 148
   Posted 11/24/2007 12:21 PM (GMT -6)   
it's kind of gross but I'll chew up some food and then stick the dose into that and then swallow it. Otherwise, I'll throw up. That taste is awful. Also, spoons full of yogurt help out too...
25 years old
Diagnosed 9/06 with Pancolitis. The diagnosis was changed 9/20/07 to Crohn's disease.
Located in my large intestines, stomach, and mouth.
Asacol 3 3x's a day reinstated 9/20/07
Methylpred 40 mg a day.

Regular Member

Date Joined May 2006
Total Posts : 167
   Posted 11/24/2007 1:30 PM (GMT -6)   
Eat it with food and it's not too bad, I try to swallow it as fast as possbile.
Male DX with CD May 2006 @ age 22, Colonoscopy and SBT
Taking Prednisone 17.5mg (tapering), Imuran 75mg (eventually 150mg I was told), Atenolol 25mg for fast heartbeat and Restoril 30mg for the sleepless nights (thanks Pred!)

Regular Member

Date Joined Jan 2003
Total Posts : 224
   Posted 11/24/2007 10:40 PM (GMT -6)   
i dont take pred anymore...but i sometimes get it with my Remicade.....when i take it i have a sucker or some hard candy ready and i just take it with water(soda makes it bubbly) and right after i swallow it b4 i even have a chance to close my mouth i put the sucker or hard candy in the back of my mouth on my tounge(it works pretty good for me)!!!
Good Luck tapering....
 "The Lord wont give me more than I can handle,i just wish he didnt trust me so much!"
  "let people be people before they are patients"

Regular Member

Date Joined Oct 2007
Total Posts : 390
   Posted 11/24/2007 10:51 PM (GMT -6)   
I could taste the prednisone when I first started taking it, and what was even more terrible was the Flagyl - it was bitter and horrible.  I realized it also had a bit of a dusting on it from the pill bottle so I started gently wiping off the pills before I took them and that helped with both of them. i also chug a ton of water and take a bite of fruit or something after I take it.

snowy c
New Member

Date Joined Nov 2007
Total Posts : 3
   Posted 11/25/2007 12:07 AM (GMT -6)   
I'm not on it now, but in the past, I've "chased' it orange juice, to cut the flavor. I'll probably be on it again after monday. sigh

Veteran Member

Date Joined Apr 2007
Total Posts : 532
   Posted 11/25/2007 12:15 AM (GMT -6)   
Welcome snowy, what happens on Monday? I also take my pred with food, OJ or yogurt.
Diagnosed at age 19 with CD.
3 small bowel resections, 1 for perforation, 2 for strictures 

snowy c
New Member

Date Joined Nov 2007
Total Posts : 3
   Posted 11/25/2007 12:20 AM (GMT -6)   
My colonoscopy. :( Basically, they're pretty sure that I've got ulcer-whatever it is- colitis or Crohn's, but my dr didn't want to prescribe something serious like pred until she sees the results. But then again, I've got classic symptoms so she's pretty sure that's what's wrong with me. I was taking pretty serious drugs for a bad accident a few years ago, so the original thought was that the meds had killed my stomach lining, but I've been off of them for nearly 6 months so I shouldn't still be sick like this.

Veteran Member

Date Joined Feb 2006
Total Posts : 842
   Posted 11/25/2007 10:21 PM (GMT -6)   
When I was taking Pred, I would put liquid in my mouth without swallowing and drop the pills in, then swallow. I only screwed up a couple times and tasted the pills...they are horrible tasting!
Crohn's Disease for a year and counting
Imuran: 150mg
Humira:finally got approval on 9/21, done with loading doses, starting biweekly schedule on 10/10
Dicyclomine and hyoscamine for intestinal cramping and spasms <--This link will be changing, but for now it works!

New Member

Date Joined May 2013
Total Posts : 1
   Posted 5/24/2013 4:16 PM (GMT -6)   
Here's a solution to the taste of prednisone:
Take a teaspoon
Pour in a little honey
Move tablet around in honey to cover it completely (I take two 50mg tabs one at a time.)
Have glass of water ready
Spoon pill into mouth and take swallow of water
Down the hatch
No ugly taste and I'm ready for the second pill.
What a relief
I need to take these blasted things for 5 days after each chemo treatment. The worst part of the whole thing, easily, was the prednisone.

Good luck all!

Elite Member

Date Joined Jan 2010
Total Posts : 10555
   Posted 5/24/2013 4:23 PM (GMT -6)   
Yeah, I know this is a nearly 6-year-old thread, but I'm still like '*** u gaiz?' Literally never noticed a taste from Pred, nasty or otherwise. The tablets are tiny and 4 at a time can easily be swallowed whole, no sweat.

New Member

Date Joined Jun 2013
Total Posts : 1
   Posted 6/6/2013 1:23 PM (GMT -6)   
Do like this: cut small rectangle (like a big vitamin swallow size) of cheddar cheese. put slit in cheese, put pill in pocket, swallow pill pocket. (my prednisolone pills are very tiny, so it's small enough to do this).
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