I've never tried the Digestive Advantage before, but I do use pro-biotics and for me, it is the best thing I have ever used. I went from having on average 10 BMs a day to once a day and sometimes once every other day. It's wonderful! No urgency, no bleeding, no pus, no cramping. Plus I'm no longer horribly anemic. My H&H are perfect for the first time in nearly 10 years. I take Multi-Dophlius 12 made by Solaray. I get it at a local health food store. My GI doc is amazed at the difference and he has been treating me for over 20 years for my severe Crohn's.