Xifraxan and Nexium?

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Regular Member

Date Joined Jul 2007
Total Posts : 70
   Posted 12/19/2007 11:59 AM (GMT -7)   
Anyone have any opinion or suggestions on these drugs?  Nothing that i have been on for 2 years has helped my rectal crohns and they are now suggesting these.  I likely will start Humira soon as well.  (Built up antibodies to remicade immediately)  Humira is the one thing i havent tried yet.  FYI, i have had bad reactions recently with both flagyl and tetracycline and i hope this wont do the same.  Please offer any advice.  Also, got the name of a Dr. Scott Harris at Georgetown that i am going to January 7th.  Anyone know of him?  Thank you and happy holidays.  I might be running to the bathroom w/ urges 30 times a day but next week ill be doing it in the Bahamas at least!

Veteran Member

Date Joined Apr 2005
Total Posts : 3763
   Posted 12/19/2007 12:15 PM (GMT -7)   
Are they Rxing these for the same issue? I'm assuming you mean Xifaxan. I have been on Xifaxan for about 1.5 years. It is an antibiotic for travelers D used off label for Crohn's. It has helped me tremendously. I don't have to run nearly as many times and actually can get to work on time most days. I have to go an average of 6 - 8 times a day down from more than 20. Nexium is for acid reflux, I think? Hence, my confusion. I take Previcid for Gerd, and it helps for that, I haven't taken Nexium.

CD 19 years offically, 29 unofficially. 3 resections '93, '95 '97
Symptoms constantly but all tests show only minor ulcerations. Currently having multiple episodes of gastritis with no known cause.

Prednisone, 6MP,Prevacid, B12 shots, Bentyl, Xifaxan.....

Veteran Member

Date Joined Mar 2005
Total Posts : 2486
   Posted 12/19/2007 12:26 PM (GMT -7)   
Xifaxin, like Zanne said, has been used with lots of success in treating traveler's diarrhea or refractory (i.e. non-responsive to traditional treatment) IBS. The good thing about Xifaxin versus Flagyl is that it only acts in the intestine and is not systemically released, so there are fewer side effects. Hopefully it will prove successful for you! And I'm also confused about the Nexium, as that is used to treat acid reflux and/or GERD.
Co-moderator - IBS Forum

Regular Member

Date Joined Nov 2007
Total Posts : 41
   Posted 12/19/2007 1:56 PM (GMT -7)   
i told my GI about my chest pain, he put me on nexium. my chest doesnt hurt anymore but i have been getting headaches alot more. the chest pain was worse then the headaches are so im going to try and stick it out for a little longer. we will see =)
Diagnosed with cd in Sept. 2007 after an E.R. visit and surgery on a fistula. Problems for as long as I can remember...


Current Meds:

Pentasa ... Prednisone ... Nexium ... NeLuv ... Humira ... Flagyl ... Cholestyramine ... Canasa ... Yasmine

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