Importance of Biopsy

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New Member

Date Joined Dec 2007
Total Posts : 11
   Posted 12/20/2007 12:28 PM (GMT -7)   
I had my follow-up appt yesterday from having my pill endoscopy.  The docotor said I had chron's and celiac disease.  Now, the question I have is he said they like to have biopsy to be certain, however, since mine was where the small and large intensine contects there was no way to reach it to biopsy.  So, I set up a second opinion, but I just wondered what everyone else went through when diagnosed with these diseases.  I asked him how he was sure then it was chron's and celiac he said the upper endoscope did so abnormal villi and that the images from the pill endoscopy showed signs of chrons and celiac.  What does everyone think?

Regular Member

Date Joined Oct 2007
Total Posts : 54
   Posted 12/20/2007 12:49 PM (GMT -7)   
I usually flare in the same areas where you have the disease. I had a colonoscopy, but I have a stricture there, and the doc couldn't get through to see it. Then, he sent me for an Upper GI/SBFT. It didn't show much inflammation there, but it did show the stricture. THEN, I was admitted to the hospital over Thanksgiving, and they did an abdominal CT scan, and it showed inflammation all over the place. I wish they would have done the CT scan first, since I had battled with the pain for months. It's always such a long process that I have to go through before the doctor will do any other treatments. Very frustrating!!
Diagnosed with Crohn's in 1995.
Have used Prednisone, Flagyl, Cipro, Pentasa, and Imuran in the past.
Currently on Humira.
One stricture in distal ileum.
No surgeries yet.

Veteran Member

Date Joined Jan 2004
Total Posts : 598
   Posted 12/20/2007 1:07 PM (GMT -7)   
He must have done a biopsy on the duodenal mucosa to diagnose celiac. If he was in there with the endoscope it would have been very unusual not to biopsy you. For the crohn's, that is the purpose of the pill endoscopy- to see areas that are not accessible from either end.
10 years, many tests, 3 gi doctors, Pentasa 1000mg 3x day
diovan, simvastatin and now trying good ol' zoloft

New Member

Date Joined Dec 2007
Total Posts : 11
   Posted 12/20/2007 1:45 PM (GMT -7)   
I have had two CT scans prior to all this and nothing showed on them.  They said I had prostratitius for several months before they did all these other tests.

Veteran Member

Date Joined Nov 2007
Total Posts : 4363
   Posted 12/20/2007 2:05 PM (GMT -7)   
If they can't biopsy with the scopes, you can ask for the blood tests for Crohn's and Celiac from Prometheus labs. It isn't 100% accurate, but if the the blood tests come back positive, it would be one more piece of the puzzle, and perhaps it would be enough to start medical treatment
48 yr. old female, diagnosed with Crohn's Sept-Oct. 2007

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