genetic testing

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Alexandria2015
New Member


Date Joined Jun 2015
Total Posts : 3
   Posted 6/30/2015 6:38 AM (GMT -7)   
does anyone know what the chances of 1 parent being a carrier of the CF gene and the other parent being negative and whether they will and what the percent number to pass on the children?

Gemsi
Forum Moderator


Date Joined Feb 2007
Total Posts : 1050
   Posted 6/30/2015 3:47 PM (GMT -7)   
There is a 1 in 25 chance of someone being a carrier of the CF gene. (uk statistics).

If you look at the full CF gene being part of a puzzle, there are 2 pieces to the puzzle. 1 piece is from each parent.

A carrier of CF has a healthy gene from one parent and a faulty gene from the second parent. A person with CF has a faulty gene from each parent.

IF one parent is a carrier and the other parent is not, then their child won't have CF, but there is a 50-50 chance their child could be a carrier.

IF both parents are carriers, then there is a 1 in 4 chance their child could have CF.

Hope this helps, tried to break it down as much as I can.
Moderator of the Cystic Fibrosis forum

Hey, I'm Gem with CF, age 29 and diagnosed at 2 years old. I'm no expert but having CF myself I've learnt a few things along the way.
Diagnosed with: Cystic Fibrosis, Asthma, ABPA, Clinical Depression, Mild Liver Cirrohsis, Mild Osteopenia, Erythema Nodosum, Proximal Myositis, Polyarthralgia

Gemsi
Forum Moderator


Date Joined Feb 2007
Total Posts : 1050
   Posted 6/30/2015 3:49 PM (GMT -7)   
Here is a diagram to make it easier to understand :)
VIEW IMAGE

Wiley Coyote
Regular Member


Date Joined Jan 2015
Total Posts : 37
   Posted 7/12/2015 5:22 PM (GMT -7)   
Unless of course, one parents caries an untested for or unidentified CF gene, and then the child could have CF if the other is a carrier. And there is also such a thing as CF -like syndrome where someone only has one identified gene, and so supposedly is a carrier, but has all the issues of CF.
CF DDf508 w/ CFRD (dignosed 3 months) 43 years old, 2 kiddos
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