It sounds like you have done all you can for your friend. She just may have to hit her rock bottom which might mean the siblings selling the family home out from under her. Then she would have no place to live and she would have to find a job. If that happens, you will have to be careful and not enable her by taking her into your home. It is somewhat like dealing with an alcoholic or an addict, the only difference is that the drug isn't there.
I wish you and your friend the very best. I know you want her to have a good life.
Hugs and prayers,
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Epilepsy, asthma, GERD, depression, hypothyroidism, tinnitus