Suicide in family / Celexa - please help

New Topic Post Reply Printable Version
[ << Previous Thread | Next Thread >> ]

Regular Member

Date Joined Jul 2007
Total Posts : 161
   Posted 2/19/2008 5:21 AM (GMT -6)   

Does anyone know if an adjustment or two in someone's Celexa dose could actually be enough to make them take their own life? We just lost a family member...she had a history of major depression and suicide attempts but seemed stable until quite suddenly, quite recently. Her husband thinks she may have lowered her dose of Celexa, then gone to the Dr. complaining of not feeling right. Dr. then doubled the dose. She was anxious, said she didn't feel right in the head, and a short time (1 - 2 weeks) after the dose increase she killed herself. We are just so lost...thanks for any input anyone has about this. - Jamie
36 year old mother of a fabulous toddler. Major symptoms began after her birth, with widespread pain/stiffness and mucus in stool. Had seen blood in stool for years prior but believe (and still suspect) hemorrhoids and/or fissures for this particular manifestation.

Diagnosed with Crohn's July 2007. The only visible areas of inflammation via scope were my stomach, rectum, and somewhere in my colon. Pill Cam, SBFT, CT Scan all normal. I think I may mainly have colitis.


On Specific Carbohydrate Diet (SCD) since late July and seeing improvement in "output" quality and hopefully therefore absorption. Taking SCD legal supplements: B vitamins, Folonic Acid 800mg, EnZym Complete DPP IV Aid by Kirkman.

Current biggest complaints: LRQ fullness and burning now gone. Gastritis symptoms are also quiet now. What was horrible right hip and low back pain has subsided about 60%. I'm pretty much feeling normal but in no way think I do not have more symptoms in my future.

Veteran Member

Date Joined Jan 2006
Total Posts : 2408
   Posted 2/19/2008 5:27 AM (GMT -6)   

Hi there,

When you adjust the dosages (particularly when lowering) on drugs like Celexa, this can be an issue. It should be said though that the risk is small and that it is not normally the drug which is responsible.


Everyone has a guardian angel. They help pick you up when you fall, comfort you through your times of need and help you appreciate the times when things are going well.
"A gold medal is a wonderful thing. But if your not enough without it, you will never be enough with it." - Irvine Blitzer (John Candy) in Cool Runnings
Moderator - Epilepsy Forum
Co-Moderator - Depression Forum
Help support the forums so we can support you:

Veteran Member

Date Joined Sep 2006
Total Posts : 510
   Posted 2/19/2008 5:29 AM (GMT -6)   
I'm sorry for your loss Jamie, quite a few of the SSRI's are known for suicide tendancies. Within days of starting Aropax I was suicidial and had to stop it straight away, prozac also to a lesser degree yet I'm fine on zoloft.

Getting there
Regular Member

Date Joined Jan 2008
Total Posts : 105
   Posted 2/19/2008 9:07 AM (GMT -6)   
Sorry for your loss Zoey. There is a warning with all ADs that there might be the propensity for suicide so care should be taken in watching for some of the more serious side effects of which one isfeeling worst and suicidal. I wish your family all the best.

Clinical depression,  Panic disorder, GERD,  Sciatica

Celexa 60mg qam,  Pariet 20mg bid,  Xanax (alprazolam) 1mg tid,  Serax 30 mg qhs, amitriptylline 30mg qhs , Percocet prn

We are more than what we do, much more than what we accomplish, far more than what we possess.

New Member

Date Joined Mar 2008
Total Posts : 1
   Posted 3/11/2008 2:13 AM (GMT -6)   
Zoey I am so so sorry! My sympathies prayers and so much more. I was searching online and came across this post. It is important to me because Celexa almost took my life. I have struggled with winter depression its a very mild form, never had suicidal thoughts before just depressed. Maybe once or twice a passing thought but it barely stayed and never did I act upon it!

Well I first tried Wellbutrin I hated it.. too many sdie effects and made me more frusterated and I didn't realize at the time but caused suicidal tendencies in me.. I had a slight overdose on the meds. So of course I went off immediality felt fine. Then winter came again and I wasl ike man I have to deal with this again! My friend then told me that she took Celexa for a year and it really helped her out. So I was like okay.. maybe this is a safe antidepressant,

Well it wasnt. Was on it for a month and things started getting hard.. more talk of suicide, the thoughts were there.. the almost actions were so close. Then of course there were some circumstances in my life that were hard.. but nothing that I hadn't dealt with before. But this time.. something snapped in me. Sunday morning, mind you I'm the sweet little girl whose a school teacher.. my parents nor I can even fathom how I did this.

Today I just struggle with broken bones in my back, broken shoulder blade, broken leg, had some lung problems thats better.. had some bleeding in my brain thats better.. and only 1/2 of my spleen they saved. But overall I am alive!!!

I told my doctor and she was no help! She almost made it sound like it wasn't the meds that caused it. And wanted to try me on something else! I am like NO! Never ever again!!! My counselor definitely understands. These drugs are not good for me.. they are too potent and caused suicidal thoughts and actions in me.

So I dont know whats up with these drugs but they just dont seem that reliable if you ask me... if someone goes on them I'd have everyone in their life and doctors and counselors watching them carefully! This for me all happened so suddenly... it was impulsive, I wasn't myself.. those drugs messed up my mind.. thats scary!!!

So my two cents worth I really can honestly believe that the drugs could have easily played a role, if not the main role! And that is just so unfortunate.. I am so so sorry.

Take care you're in my thoughts...

I am sorry but I had to edit your post due to Rule #1 of our forum. Please review these rules:

Post Edited By Moderator (ShynSassy) : 3/11/2008 5:05:01 AM (GMT-6)

Regular Member

Date Joined Mar 2008
Total Posts : 89
   Posted 3/11/2008 8:57 AM (GMT -6)   
I'm sorry for your loss Zoey,

Unfortunately, as some have stated above SSRI's do result in major problems. And some docotrs are researching them further. However, many doctors, psychologists and psychiatrists don't know some of the major adverse effects to these drugs because they only go by what the pharmaceutical companies say about them. Unfortunately many times even the FDA who approves the drugs (does not test them) don't get all the clinical trial information on the adverse side effects from the pharmaceuticla company.

I posted a site below that you may find interesting and helpful. If you scroll down to the bottom of that site (complete index area) you will see different SSRI's drugs and some of the problems that have already brought about litigation. You can click on any of them. Also you can look on page 2 of the cymbalta topic under depression, I posted a few more sites there on SSRI's., and more information.
Dr Breggins who is a psychologist and has been for years has been doing extensive research into SSRI's and has even fought for the families rights through litigation.

Just copy and past this in your URL. Hope its helpful to many of you.


Regular Member

Date Joined Mar 2008
Total Posts : 89
   Posted 3/11/2008 9:03 AM (GMT -6)   
4. No advertising or links to advertising or "Spam" is permited (including signatures).
· Advertising or Spam is defined as posting a link for the purpose of selling, soliciting or promoting by someone that has ownership or other "vested interest" to the web site involved, including efforts to promote other online forums or web sites by web site owners.
· If you are a web site owner and have a link that fits into this category that you want to share, please submit it to our resource directory and we will review your submission.
· Posts and links about fundraising (including nonprofit fundraisers) are NOT permitted.
· Only links to personal home pages are allowed in signatures and member profiles. Links must be appropriate and abide by rules #1-4 or they will be removed.
· Links to helpful web sites (commercial or otherwise) are allowed when they are posted by someone without any "vested interest" AND whose purpose is NOT to solicit, advertise, promote, fundraise, etc.

Pressing,sorry but I had to edit your post..please review the rules of our site.

Post Edited By Moderator (ShynSassy) : 3/11/2008 5:06:57 PM (GMT-6)

Regular Member

Date Joined Mar 2008
Total Posts : 89
   Posted 3/11/2008 9:25 AM (GMT -6)   
As MCoving said the doctors always blame it on the fact that the person was already depressed suicidal etc..thinking of suicide and actually performing the act are two different things.

These SSRI's drugs are synthetic chemicals and they affect your bodies natural chemistry whether it happens immediately or at a later date. They present extra chemicals that affect your body both positively and negatively at the same time, if you have enough of one of those natural chemicals in your brain then its absolutely going to affect you in a negative way, by overdosing your body with the chemical that is already present. This overdose of chemical can send your mind or body soaring with adverse affects.

Any doctor knows that when you affect one receptor your affecting others in the process. Giving you and SSRI drugs affects not only serotonin receptors but also dopamine, epinephrine and others. The body works as a whole you can never just treat a single area and expect only that area to be effected, with see this with regular drugs in the medical field. They give you something for your bowels and you end up with other adverse body effects, even to the point of malfunctioning.

Sorry, I do get a bit heated with this subject, I am a nursing student and am very much amazed by how the body works. I am also amazed at how ignorant some doctors, psychologists and psychiatrists are, their excise is we have the weigh the pros with the cons, if the cons are worse then we have to give meds; however, some people only have surface issues and rather than dealing with those issues, Drs. pull the pen out for a quick fix of medications, the problem is meds often just mask the problem only to have the individual have to deal with it later but not only that now but also all the negative effects of the drug.


Regular Member

Date Joined Mar 2008
Total Posts : 89
   Posted 3/11/2008 9:32 AM (GMT -6)   
Here is an interesting email I received from my last psychology teacher who also has her own practice. I will leave her name out for the sake of privacy.

My question to the psychology teacher.
My other question is in regards to serotonin. When you were speaking about ecstasy in class, you mentioned that it adversely affects the serotonin level in the brain if taken for a period of time. To the point in which serotonin levels will never return to the prior state.
Is serotonin affected not only with ecstasy, though that may be more severe but also with other SSRI drugs in the same manner? Such as with the use of Prozac, Zoloft, Paxil, etc..
Can these drugs in adversely affect either the release of the chemical serotonin or destroy the postsynaptic receptors? I was just thinking about that in regards to the nervous system, since every nerve we will ever have we obtained during infancy. Nerves themselves don’t grow like other cells in the body, though some can be repaired by the shawann cells in the axon if close enough when cut; however, not without some damage remaining.
I know someone who has a loss of some nerves in the brain due to extreme drug use, so its been boggling my brain a bit as to what the long term affects of even lower doses of synthetic chemicals could do in that respect.
I know many receptors in the body are protein derived, so I was just pondering on whether nerve receptors are the same in that respect and if a change in diet or something of that sort can actually replenish such receptors. You wouldn’t happen to know if there is any research in that area, would you?

My psychology teachers email response.
Subject: RE: Questions Sent: October 14, 2007 10:02 AM
Glad that all is well, and I hope that you found what you were looking for in that house!
Now, to your question:
SSRIs. You are quite observant to note that the SSRIs might be chemically problematic. While they do not destroy the receptor sites, there is some concern in the community that we foster chemical dependence, in a sense, in that the brain will no longer produce as much of a neurotransmitter on its own once we start introducing SSRIs. The research has been mixed as to whether this is really the case or not. My philosophy is that anything that you are putting into your body is going to have some kind of consequences, so you have to think long and hard about whether you can handle both the positive and the adverse, should they occur.
The research on homeopathic work to rebuild damaged receptors is in its early infancy. There is some current work looking at Sam-E as a possible nutrient that may contribute to neural repair, but results have been mixed thus far.
Hope that helps. I can see you have a keen interest in the brain. You would enjoy a class on neuropsychology! Have a great week and happy studying!

That was nice coming from a psychology teacher.


Regular Member

Date Joined Feb 2006
Total Posts : 344
   Posted 3/12/2008 7:17 PM (GMT -6)   
Hi Zoey,

I'm terribly sorry to hear about your loss. My deepest sympathies are with you. But, as someone who is currently on Celexa and has had tremendous success with it, I have to say that not all meds are made for all people. I also think it's always important for everyone to take medication as prescribed and not try to self-medicate themselves with playing around with doses. I hope you find some comfort here on HealingWell.

Elite Member

Date Joined Jan 2005
Total Posts : 24909
   Posted 3/13/2008 4:14 PM (GMT -6)   
I am so sorry for your loss as well Zoey......thoughts and prayers are with you and your family ..

I also do hope you find the support and caring here as great as I have in these times .......

**I TOTALLY agree with Sad on the meds and self medicating raising lowering doses**
  DX With Crohns,Pyoderma Gangrenosum, Anxiety/ Panic and Other Disorders
         Mod for Alzheimer's, Anxiety and Panic and Co Mod for Crohns Donate today to keep HW helping others

New Topic Post Reply Printable Version
Forum Information
Currently it is Tuesday, September 25, 2018 12:36 AM (GMT -6)
There are a total of 3,006,332 posts in 329,327 threads.
View Active Threads

Who's Online
This forum has 161827 registered members. Please welcome our newest member, a8166008.
131 Guest(s), 3 Registered Member(s) are currently online.  Details
borrelioburgdorferii, Matthew Sleeman, Girlie