Welcome to HealingWell and the Depression Forum. You will find the members here to be extremely caring and supportive. I have had depression for 28 years and I know where your coming from and what you are going through.
Losing the friendship of one you trusted for 10 years is sad and you have a right to feel depressed about that. Is there anyway you can mend this friendship?
We all want to be liked and respected. Most of us have an inborn trait to be kind and we do our best to be a good friend yet there are times when things do go wrong and friendships are lost. This is very painful but remember you are still a good person and I am glad you found this forum.
If you have not done so already you may want to make an appointment to see your PCP and have a physical and talk to your PCP about your feelings of depression. There are many treatments for depression and you may do well with some therapy to help you build up your self esteem and help you to learn how to deal with your depression.
Keep posting and again welcome to HealingWell.