Hi Eli, I believe I answered your other posts about taking remeron which I take. Do give it four to six weeks to fully take effect. Are you increasing your dose over these weeks? Once you are up to full dose, 45 mg I think you will really feel better. As I have said I tried about 6 different a/d meds before the remeron and that was the one that truly helped me. So give it time and I think you will notice the difference. If you are not having any bothersome side effects it will be worth the wait. Keep me posted on how it goes.