hi waterfaller. welcome.
me, went of 375mg effexor xr, 4 pristiq, 4 months ago. pristiq is a derivative of effexor, less sedating, moreover the weaning process is only a few days. i find pristiq to be excellent. good as an anti-dep!! takes a few weeks to start kickin' and after the required 6wks pristiq starts to aid in base-line depression. hope this helps, jamie.
dx mdd, severe borderline personality disorder.