help with antidepressants

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New Member

Date Joined Jun 2009
Total Posts : 17
   Posted 6/20/2009 9:41 AM (GMT -6)   
Has anbody had an experience with anti depressants
working temporarly and then having to change. Up till the last year I had been on Effexor which worked great for me. In the last 6 months I have been on Lexipro, Zoloft, Cymbalta, Remeron and now Prozac. I have gone through alot of trauma over the last few years and I know my body is reacting to that . Plus I am in the wonderful world of menopause. Also has anybody had a positive experience with Ambilify and an anti depressant?. I know everybody's body is different but it helps to hear others experiences. Thanks, Duck

Post Edited By Moderator (getting by) : 6/20/2009 9:28:30 AM (GMT-6)

getting by
Forum Moderator

Date Joined Sep 2007
Total Posts : 42609
   Posted 6/20/2009 10:27 AM (GMT -6)   
Hi Duck,

I take abilify, effexor and xanax. I had wonderful results when the abilify was added. I hope that it works for you too. I am going to give your post a topic. I hope that you don't mind.

Hugs, Karen
  Moderator-Depression and fibromyalgia
fibromyalgia, Chronic fatigue, depression,allergies

Elite Member

Date Joined Mar 2009
Total Posts : 20279
   Posted 6/21/2009 3:16 AM (GMT -6)   
hi duck, have been on the anti-dep misery go-round for 20 plus years. recently transitioned from effexor xr, 4 yrs, to pristiq. have used abilify also, it is known more as a as, but is effective in combination with certain ad's as a effective mood stabiliser. helps with cognition and thought processes. hoping you find the right meds. can be a difficult process, as i found out!!! keep fightin, here for you. jamie
dx, mdd, severe borderline personality disorder.

Forum Moderator

Date Joined Oct 2008
Total Posts : 7348
   Posted 6/21/2009 6:55 AM (GMT -6)   

I have been on 5 different antidepressants over the last couple of years and have still to find one which really works for me which is frustrating, I am currently on 225mg of Effexor. I hope you find something soon which helps let us know how you get on.

Take Care


New Member

Date Joined Jun 2009
Total Posts : 17
   Posted 6/21/2009 7:34 AM (GMT -6)   
Thanks for the input everyone. I am sorry for your struggles but at the same time it helps to know that I am not the only one. I guess I was just very lucky when Effexor worked for me for so long. I will consider the Ambilify. Have you had side effects from Ambilify? Again I know everybody's body is different Duck

Elite Member

Date Joined Apr 2007
Total Posts : 32602
   Posted 6/21/2009 7:48 AM (GMT -6)   

Hey Duck,

For years, many, many years I did excellent on Nortriptyline, a second-generation tricyclic antidepressant.

In 2005 the medication started to poop out even though we increased the dose.  If your on this med many physicians require blood work to check for therapeutic blood levels and even with labs showing good levels the med quit working or something changed.

In November of 2005 I had a major melt down and ended up taking early retirement from my job.

After that we did the antidepressant two step and I danced with many of the SSRIs and ended up on Cymbalta for a year or so but nothing every really worked like the Nortriptylinne. I had reactions to Imipramine and to Serzone both causing me to end up in ER, one an overnight hospital stay.

I just did a slow wean off of the Cymbalta and it has been 2 months now.  I feel like if I could just find a med at a low dose that would even things out I would be better.

For now I use Trazodone 100mg at HS which helps with the insomnia and Buspar for anxiety. 

I understand how difficult it is to keep on trying to find a miracle medication but for me it seems I must work through the issues without an AD per se.  

I hope that you are able to find a good combo of medications that work for you.

Take care and gentle hugs


Elite Member

Date Joined Mar 2009
Total Posts : 20279
   Posted 6/22/2009 4:35 AM (GMT -6)   
duck, the abilify actually brought me back from a very bad state, so the effects on this one are in the positive, yeah we are all different, keep fightin' the good fight! jamie smilewinkgrin
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