hi karen, am on 200mg of pristiq. i am up and down with my depression, today i thought about
changing possibly to prozac, but i have been bouyed again. for me i find the pristiq much less sedating than effexor, and with proper sleep patterns the stuff actually works, furthermore if you stay positive i feel that it
opens up the synapses and does a better job at correcting the imbalance. i have had no real side effects, if anything my body is becoming more regulated, and my doc says that pristiq is a far better long term option for me also. my metabolism is far better on pristiq, and i have more energy on it than effexor, thus i have lost good weight, and this morning my bp was perfect, something i have always had trouble with. so all good. so a big tick for pristiq.