I'm glad to find a recent post to this! There is HOPE. I believe from experience you can return to your happy non-depressed, non fluctuating "normal" state of mind.
My 1st Depo shot (Planned Parenthood)was September 2011 and I experienced extreme emotions that I had a gut feeling was from the shot. I was an already moody person in my cycle but not to the point of crying from normal stress until the Depo Provera shot. Emotional pain was magnified and break-up/arguements felt more cruel and unfair than usual.
My 2nd Depo shot (Planned Parenthood) Fantastic! I became an Early Bird! I could do overtime for work like I was a machine and barely even feel it, then go in and pound away again. More energy, less distracted. I took benadryl though to be able to sleep at night. Insomnia is definately part of the package with super early bird reaction. That is above my normal state, as I am a night owl naturally.
My 3rd Depo shot (Jan-March 2012)was solitary confinement. Just a day after the shot, it was like BOOM, I'm depressed and empty isolated feeling...the night before my birthday! I mean my birthday is on St Patricks day and always some fun bubbly dance of the Irish I could be doing but nope, lost the drive To drive or go anywhere. I made myself call a friend because I couldn't go down like that for my b-day. Company helped, but it was just the begining. I had no idea where the finish line was out of the "emotional slum of unpredictable random sense of self"! It was the most challenging inner battle I've ever gone through because I didn't understand the "why is this me now?" "what can I do about it" and "when does it end". With the economy the way it is, I just thought the moods of the world were finally catching up with me.
My "Intermission Point of Peace" happened about 2 1/2 months into 3rd Depo shot I referred to above. What gave my brain a doorway is an article I stumbled upon about Therapy - We can Take Control because we are not to blame, and we can choose to rise above it. My attitude changed because I realised I had a right to love, health, happyness etc, I owned up to feeling crappy and trampled on by friends and lovers. This is just an example of so many turns my mind was able to make. I grieved, my spirit cried, I went to sleep, and felt carressed by a caring embrace inside. I knew then, it was going to be ok. The next day, the love for myself was there again, love for life, appreciation of others, thankfulness of making it out of the "dark disconnect" feeling.
4th Depo Shot (Private Doctor) Extremely Positive so far, like the 2nd Shot was, only better . I was instantly motivated and hyper rather than tired and unmotivated! Feels like a Depo shot build with drugs to counteract the Depo Provera common symptoms like Adderall or something. Insomnia though gets me. I fight off sleeping until the 3 hours of possible sleep decision has to be made. Then, I have to force myself down. Can hormones do this? Either way, I believe there is a link between what makes the mind not want to sleep and Depo shot because there are TWO extreme sides. I've never actually seen the Box of Depo...It's always some Medical Assistance with a clear, non-labeled needle ready to stick me with...(laughing at this). So, who knows, but there IS HOPE. Part of the way out is knowing you are able to get out, and you are loved.
5th Depo? um NO. See, the pattern above shows that either Ovulation is better suited for Depo on one ovary side than the other, or my body balances me with a crappy Depo shot to make up for my superwoman depo the time before...OR it's NOT always the same Depo "Brand"...a generic Depo Provera might be your world of trouble so I would ask your doctor to get you the real deal if he/she hasn't been giving you what you think. Have you seen the box? Just saying...there's alot of different "hydrocodone" manufacturers and they are not all the same effect, for example.
Hang in there...don't forget to post when you're feeling better too!