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Ugh Just Ugh
Veteran Member

Date Joined Jan 2010
Total Posts : 1004
   Posted 5/7/2010 1:10 PM (GMT -6)   
Hi, there! I'm from the UC forum but am going through a tough time and recently start taking Lexapro 10mg. I was on it for about 2.5 weeks and really felt like things were going in a positive direction. My doctor added Trazodone 50mg at bedtime to help with sleep and augment the Lexapro. Once I hit about 4 weeks on Lexapro and 7-8 days on trazodone I got really whacked out. I *think* I might have seratonin sickness/syndrome. I stopped the trazodone after 10days and figured it wouldn't be a problem because it was a small dose. I also skipped one dose of Lexapro figuring I need to get some of this excess seratonin out of my system pronto. I'm feeling better today than I did yesterday, but still not 100%. Here's my question: after being on Lexapro for 4 weeks can I just quit cold turkey or should I be tapering down? Thanks for any help/insight!
Originally Diagnosed: 7/08 Mild left sided UC
Current Flare started 12/26/09: Severe Inflammation through Entire Colon, some patchiness indicates might be Crohn's.
Current Meds: Prednisone 30mg, Imuran 150mg, Lexapro, Trazodone.
Past Meds: Mesalamine Enemas, Canasa Suppositories, Hydrocortisone Enema & Supp. Asacol.
Suppliments: Multi, Fish Oil, C, Iron, D, Calcium, Potassium, Bio-K.

getting by
Forum Moderator

Date Joined Sep 2007
Total Posts : 42612
   Posted 5/7/2010 2:33 PM (GMT -6)   
Hi Ugh,

It doesn't seem like you have been on it a long time, but really you should ask your doctor about this. 10 mg of lexapro is the usual starting dose. But I would still ask the doctor. It is much safer that way. There are other meds like celexa, effexor and pristiq. I think lexapro is an ssni instead of ssri, but not positive, but it is suppose to be a close cousin to effexor and I was on that for many years at the highest dose that you can take. The side effects, if that is what it were to be, should be wearing off soon.

So I can't say if it is safe or not, I honestly would speak with your doctor before stopping any med.

I truly hope that you feel better soon.

Hugs, Karen
  Moderator-Depression and fibromyalgia
fibromyalgia, Chronic fatigue, depression,allergies

Veteran Member

Date Joined Nov 2008
Total Posts : 2859
   Posted 5/8/2010 5:48 PM (GMT -6)   

Hi Jennifer...Like Karen said it's best to talk to your doctor.  Please do not stop this drug cold turkey, however....even though you have only been taking it for a short time.  Some people are very lucky and can start and stop SSRI's with little difficulty.  I was NOT one of those people.  My doctor told me that I would not have any withdrawal symptoms after being on 10mgs for three was such a 'small dose'.  Uh, wrong.  If your doctor advises a taper, do it slowly by cutting the dosage down by 1/10th a week.  That is the official tapering schedule for this drug, no matter how long you have been on it, according to Forest Laboratories. (I actually called their medical professional they have on call as I could not figure out what was going on with my body after just stopping.  I wish they had put this in the info they give you when you start the drug).

Hope this helps and you feel better soon.


fibro, menieres disease, RLS, anxiety disorder, disc compression, scoliosis, spinal stenosis TMJ  Meds: valium Advil

Elite Member

Date Joined Mar 2009
Total Posts : 20279
   Posted 5/9/2010 5:42 AM (GMT -6)   
definately taper off. not just lexapro but with all meds. i did the cold turkey thing once, geez, i regreted that massively!!!!! never again. keep talking with your dr. all the best, jamie.

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