Seroquel at night

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Veteran Member

Date Joined Dec 2008
Total Posts : 4961
   Posted 7/31/2010 7:32 AM (GMT -6)   
Hi all-
I have been taking Seroquel at night to help with sleep. I was wondering if anyone else who takes or has taken this has a hard time waking or feel very unsteady when walking if you don't get to your sleeping place fairly quickly?

Take care,
Moderator: GERD/Heartburn
Nissen 6/06 and 5/09

getting by
Forum Moderator

Date Joined Sep 2007
Total Posts : 42609
   Posted 7/31/2010 8:10 AM (GMT -6)   
Hi there,
I don't take seroquel, but wanted to welcome you to the forum, if I haven't already.  I don't remember seeing you post here before, but that doesn't mean anything because I get fibrofog and I can't remember things.  Story of my life. lol...
You will get some advice I am sure.  But being it is the weekend, it is sometimes slow here, so it may be Monday before you get more information on this medication.  So do hang in there.
Keep posting if you feel like it, know that everybody here is very kind and compassionate, and we do understand.
Hugs, Karen
  Moderator-Depression and fibromyalgia
fibromyalgia, Chronic fatigue, depression,allergies

Regular Member

Date Joined Jul 2010
Total Posts : 71
   Posted 7/31/2010 8:24 AM (GMT -6)   
I used to take seroquel to sleep for a year ish. Don't know how long you've taken it, but the most common side effect (says my doctor) is weight gain. Be aware of that, watch your appetite. I gained 30 pounds overall from that and Zoloft combined.
Anywho, back to your question: Yes, if I didn't get enough sleep I had a heck of a time waking up in the morning and I was irritated. Also, I took this at night, but when I didn't get at least 10 hours of sleep I was groggy in my classes and either falling asleep or just being irritable because I was tired. My teachers did NOT like me that year. I'd just be aware that if you only allow like 7 or 8 hours for sleep, with seroquel, that won't be enough I don't think. Unless you don't mind waking up drowsy and irritable.

“Even if you’re on the right track, you’ll get run over if you just sit there”

horse crazy
Regular Member

Date Joined Feb 2010
Total Posts : 199
   Posted 7/31/2010 8:55 AM (GMT -6)   
Bill...I take 200mg of seroquel at night and it definitely makes me very sleepy.  I get all ready for bed before I take it, because once it kicks in, I better be close to my bed.  I am very unsteady after it starts working.  But it seems to be a decent drug.  I have a bit of a drug hangover in the morning but it is short lived.
Horse Crazy
Bi-polar I; rapid cycler; Lithium 600
Methadone 5mg (for restless leg syndrome) Lamictal 200 mg; seraquel 450mg, klonopin 4mg

Veteran Member

Date Joined Mar 2008
Total Posts : 3089
   Posted 7/31/2010 10:00 PM (GMT -6)   
Hi Bill,

I take seroquel XR at night (currently at 150 mg & have been on it for about a month) as an antidepressant adjunct/for poss bipolar II, and although it does not make me sleepy or tired the next day, the side effects you describe are very common.

Recently, I forgot to get a prescription from my doc (he had previously been supplying me with samples) & I ran out of the meds I had on hand over the weekend. Fortunately, my father is a physician & he was able to bring me home some more samples from his office, but he did not have any of the XR on hand. As such I had to take the regular seroquel (not the XR that I normally take) for a few days & I did notice a big difference. My father told me that there was little difference between the XR and the regular, but the regular seroquel made me very lethargic and unsteady.


Veteran Member

Date Joined Dec 2008
Total Posts : 4961
   Posted 7/31/2010 10:29 PM (GMT -6)   
Thanks for the welcome. You know I am not sure if I have posted here before or not. LOL

Thanks for the replies. I am glad it is a common side effect and not just me. I definitely have to get 8 plus or I am very tired still.

Take care,
Moderator: GERD/Heartburn
Nissen 6/06 and 5/09

Elite Member

Date Joined Mar 2009
Total Posts : 20279
   Posted 7/31/2010 10:39 PM (GMT -6)   
me 1200mg. has pooped a bit, been on it 7yrs. just started taking melatonin with it. much better upon waking. use to wake up alike the walking dead, and need a plethera of double coffeees to get me movig. take care, jamie.
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