Antidepressant Advice

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Regular Member

Date Joined Aug 2006
Total Posts : 47
   Posted 8/25/2010 9:38 AM (GMT -6)   
Trying to decide if I should be taking Celexa, Lexapro, Prozac or what for depression and anxiety. I do not want to gain weight. I had been on Paxil at one time (dr. told me it didn't cause weight gain, what a load of crap that was) then on Prozac (lost a bunch, had enormous carb cravings, gained it back plus more What should I try???

getting by
Forum Moderator

Date Joined Sep 2007
Total Posts : 42611
   Posted 8/25/2010 9:40 AM (GMT -6)   
Effexor and Welbutrin are suppose to be weight neutral. Talk to your doc about them. Especially the wellbutrin, most people lose weight on it.

Best wishes, Hugs, Karen
  Moderator-Depression and fibromyalgia
fibromyalgia, Chronic fatigue, depression,allergies

Regular Member

Date Joined Jul 2010
Total Posts : 71
   Posted 8/25/2010 12:16 PM (GMT -6)   
Celexa landed me in the hospital with a psychotic episode, I strongly discourage the use of that medication. I haven't heard a lot of similar experiences like mine with the drug, but it really was the worst experience of my entire life. I had no control over my body or mind. I was trapped in a terror and it was extremely serious. I've always been a pretty even tempered person, so when that happened needless to say it was unexpected. Nothing like that has happened to me since, so it was clearly the drug. I've heard good things about Lexapro..don't believe it causes weight gain in a lot of people, but I can't be 100% sure on that. I only know about 3 people who've taken it. I take the generic Klonopin as needed for anxiety. No weight gain with that. Your body does get used to it over an extended period of time, so it's not one of those drugs you can use for years and years without upping the dose.

"Dreams don't always have to exist while the sun's down
and your eyes are shut."
-Alex Gaskarth

Regular Member

Date Joined Jul 2010
Total Posts : 89
   Posted 8/27/2010 8:51 PM (GMT -6)   

Celexa and Lexapro are very similar drugs. Lexapro is supposedly a cleaned up version of Celexa with fewer side effects. Having been on both, I don't buy it. I actually felt better on the Celexa.  The Lexapro really didn't do anything for me. Pristiq is another sleight of hand by the drug companies. It's nothing more than a metabolite of Effexor. Effexor is venlafaxine and Pristiq is desvenlafaxine. It seems awfully strange to me that these "cleaned up" drugs come on the scene at the very time the parent drugs are going off patent and thus available in cheaper generic versions. 

Anyway, to try and answer your question, it seems to me that all (and I've been on them all) SSRIs can cause weight gain.  I'm on venlafaxine (Effexor) now and I'm still a little on the heavy side. It is true that the only antidepressant that doesn't cause weight gain (and can even cause weight loss) is Wellbutrin. But Wellbutrin isn't the best medication for someone with anxiety or panic disorder. It is a very stimulating antidepressant. But it may well work for you if you're on a counteracting medication, such as a benzodiazapine.

The older tricyclic antidepressants are awful for causing weight gain, and fast.  Your best choice is the newer meds, and trying to keep carbs down and exercise up. 
None of these medications are perfect by any means, but they do help a lot with varous disorders.
As always, none of us here (as far as I know) are doctors, so please discuss all options with your doctor to try and find the best medication for you. There are many medications, and many are mixed to try and get the best effect. It's all trial and error, really. What works well for one may do nothing for another, and vice versa.
Lastly, sometimes we have no alternative but to live with the extra weight. A few extra pounds is infinitely better than crushing depression and anxiety.
I hope you get everything sorted out and feel better soon.
God bless.

Post Edited (G20man) : 8/28/2010 2:03:22 PM (GMT-6)

Veteran Member

Date Joined Jul 2008
Total Posts : 2317
   Posted 8/27/2010 10:13 PM (GMT -6)   
I lost weight on Wellbutrin. But it's not for everyone. Definitely wasn't for me. But maybe you can talk to your doc about it.

spinal soldier
Veteran Member

Date Joined Dec 2009
Total Posts : 687
   Posted 8/28/2010 3:06 PM (GMT -6)   
L4,L5,S1 bilateral Laminectomies, Foraminotomies 2002
L4-S1 PLIF with instumentation 2008

current Rx: MScontin 100mgs 2x, dilaudid 8mgs 4x p.r.n.phenergan 25mg 3x prn, cymbalta 60mg 1x,Adderall 20mgs 2x zanaflex 4mg 3x, relafen 1000mg 1x, xanax 0.5mg 2x prn

getting by
Forum Moderator

Date Joined Sep 2007
Total Posts : 42611
   Posted 8/28/2010 3:26 PM (GMT -6)   
Hi Spinal Soldier,

I just wanted to welcome you to the forum as I haven't noticed you here before. I couldn't help but notice your signature. It looks like you could be in a lot of pain and for that I am sorry. Just wanted to mention that. I hope that you are having a good day today.

Hugs, Karen
  Moderator-Depression and fibromyalgia
fibromyalgia, Chronic fatigue, depression,allergies

New Member

Date Joined Aug 2010
Total Posts : 2
   Posted 8/29/2010 9:20 PM (GMT -6)   
I became suicidal on Wellbutrin but over time one seems to "pop out the other side" of any antidepressant drug. I'm on Celexa now having gone off Lexapro for about 2 years. I was in despair and really ready to end it all before 5 years on Lexapro. Then clean for two years but began to feel profoundly unhappy (a real diagnosis I guess but I just made it up to tell my doctor how I felt). He put me on Celexa and I do feel happier. But, although all the SSRs hit your libido to some extend for ever or for a while, I immediately went into total anorgasmia coupled with ED from cancer. I remember longingly those days of planning to  but I just feel to good to take it seriously now. Still, I really miss sex. Call me shallow, but the company, conversation and attention of beautiful women - and sex - was my life. What am I here for now? But enough about me. All the antidepressants have the risk of making you fat or thin, horny or disinterested, sleepy or insomniac, etc. Seems like everyone has a different reaction and side effect. The Psychiatrists know less about any of this than you do, I expect.  Nobody has a freaking clue. Trust me. It's ALL trial and error. Church, real hobbies, a special someone can do more for you than all the pills in the world. A good bourbon can go a long way if not abused (That's the trick). Even a has helped some though it makes things much worse for me. But, the bottom line, it's still in the voodoo stage with "doctors" in "costumes" mumbling enchanting words and handing out special herbs, in my opinion.

Post Edited By Moderator (getting by) : 8/30/2010 7:41:38 AM (GMT-6)

Veteran Member

Date Joined Nov 2008
Total Posts : 2859
   Posted 8/30/2010 7:57 AM (GMT -6)   

All these drugs that are handed out like candy 'poop out' after several years of use.  Your doctor will be quick to tell you it's your old symptoms returning and pump up the volume or convince you to start on yet another drug. Lexapro w/d almost killed me, as no doctor ever heard of 'tapering slowly'.  I am still suffering 10 months later after going cold turkey, per my doctors instructions.  (I was on such a low dose I wouldn't have w/d's...uh, no).

Listen to your body and and if something does not feel right, or you have symptoms you never experienced before...find some kind of medical professional that will listen, and not blow you off.  And yes...despite the assurance I would not gain weight on the drug, I gained 22 pounds in the first six months.  Oink...

I'm staying away...far far away but acknowledge most people will not suffer like I did and these drugs can be life savers.


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