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New Member

Date Joined Nov 2010
Total Posts : 2
   Posted 11/3/2010 1:56 PM (GMT -6)   

Have Treatment Resistant Depression. Tried numberous ADs. Coming off of Effexor after a failed trial. Last 6 months have tried Remeron, Cymbalta and Effexor. Also tried other classes of ADs. Need hope. Drs are not sure what to do now. Scared of anitpsychotics though I use Zydis for sleep at a low dose. Don't want ECT.

Has anyone ever gone off an AD, especially Effexor and actually did better?

Side effects of Effexor have been headaches, electocution sensations, ringing in the ears, apathy and amotivation, muscke twitches of face, and limbs, worseninganxiety and depression.

I might have to beat the "black dog" on my own. Has anyone successfully done this?


Trying to Understand
Veteran Member

Date Joined Sep 2010
Total Posts : 776
   Posted 11/4/2010 5:34 AM (GMT -6)   
Have Treatment Resistant Depression. Tried numerous ADs. Me too.

If you don't take Effexor at exactly the same time everyday, you will physically know it. Coming off it is a LONG process, not just a few days lower dosage. Have heard from someone else that they switched to regular Effexor for weaning down because it comes in smaller increments. Did I say it is a long process? Don't rush it. Sometimes docs give Prozac to help in the weaning process. Call and ask, leave a msg.

If you are going to attack this on your own, or even if you do stick with your doc/therapist, I highly recommend reading.You probably know all there is to know about depression and BP already.
To get fresh insight in what to DO, subscribe to Julie A. Fast blog, search her sight up and down to read all the free advice she offers.
Also Therese Borchard, great blog. She even has short videos sometimes, is very funny but then serious on video.
The book "The Feeling Good Handbook", by David D. Burns, a classic for mental HEALTH. Reframing mental patterns, thinking differently helps manage anxiety, depression, and manage life better. His list of cognitive distortions is an eye opener. Get it used on Amazon. It is a classic self-help book.

So far I am doing fine. Better in fact, don't know why for sure. Got a zillion vitamins that I read might make you depressed if you have a depletion. Took them for a month and so I am sure I don't have a depletion. Corrected my diet, no caffeine, alcohol, white sugar or flour. more whole foods. Working on exercise. Sun and fresh air even in small bursts during the day are healing. Learned to meditate. See: Meditating when you are feeling well is good because you will know how to do it when you aren't, and it helps.

My best self-help site is
There is so much info there it could keep you busy forever. Especially check raising emotional intelligence, depression, Depression self-help tools and coping tips.

I also feel that doing these things while I am feeling this good is necessary now because when I am feeling bad, I don't care or want to.

I have a printed list of 33 Tips and Tricks on managing bipolar by Julie Fast, and the list of the top 10 cognitive distortions by David Burns. I highlighted the ones I need to think about Keep it on my desk at the bottom of the pile. Also Meditation techniques from that site. Always know where they are at that way.

Do a print-out of this info I have given you. You will get to it eventually. And it will make you healthier, but not "the cure". Be careful.

Make a list of things you can do to stay healthy. Another list of things to do if you are slipping. Evaluate yourself and keep a mood tracker.

I figure all it is a phone call to get in to see my GP for antidepressants, or the psychiatrist if it is really bad, freaky. I have had some hypomania, but have learned how to control it so I don't do damage. The other thing is I have some hysterical belly laughing, better than crying, but it feels kinda weird. Of course after being in bed for 8 mos.

Shoot the darn Black Dog !
Severe depression

Elite Member

Date Joined Mar 2009
Total Posts : 20282
   Posted 11/4/2010 5:36 AM (GMT -6)   

hey blondie,

have been on just about every anti-dep out there.

formerly, MDD, RE-DX WITH BP-1 RECENTLY. also live with

severe borderline personality disorder. there are heaps of

other meds that may help, like abilify and some anti-

psychotic medications as well.

pls get to your dr. and or emergency dept.

i am extremely worried about you. these feelings are

highlighting that you are at risk, pls be brave and seek some

immediate assistance.  sending compassionate thoughts

your way. know that we care and understand.

jamie, male, 38.



Trying to Understand
Veteran Member

Date Joined Sep 2010
Total Posts : 776
   Posted 11/4/2010 6:39 AM (GMT -6)   
Sorry if I missed your current symptoms. Thought you were having side effects from withdrawal. And under the care of a pdoc.

If I was wrong, please take Jamie advice and go for medical care. Don't play with it.

New Member

Date Joined Nov 2010
Total Posts : 2
   Posted 11/4/2010 12:18 PM (GMT -6)   
Thanks everyone for your support.

I'm seeing the Psychiatrist tomorrow. I am actually going to recommend a drug and hope he supports me. Since I need an AD that sedates me (my depression has extreme insomnia), I'm going to ask for Trazadone at a higher dosage than they're giving me presently. It's low and Rx for sleep only at this time. I understand that it is an AD at higher dosages. He may also have another idea. We'll see.

Thanks again.

Regular Member

Date Joined Nov 2010
Total Posts : 104
   Posted 11/4/2010 2:38 PM (GMT -6)   
Don't like Trazadone as it gave me severe heart palpatations. I take Setraline which I find calming and I don't get the up's and downs with it. Have gone from 150 mg's 2 years ago to 50 mgs which is lower than the recommended dose for Depression sufferers. I suppose I could say my Depression is getting better after 23 years with it!
Fibromyalgia, Depression, Memory problems, Psoriasis, Hiatus Hernia, Asthma, Anger problems, Osteoarthritis, Fitness Problems, IBS, Pituitary Glandular problems!

getting by
Forum Moderator

Date Joined Sep 2007
Total Posts : 42612
   Posted 11/4/2010 2:39 PM (GMT -6)   
I highly recommend the book Feeling Good, the new mood therapy by Dr. David Burns that Sandy mentioned. It is very helpful. And yes, you can get it cheap used. If nothing else, get the book. It will really help you.

I hope that you are feeling better. Let us know how your appointment goes.

Hugs, Karen
  Moderator-Depression and fibromyalgia
fibromyalgia, Chronic fatigue, depression,allergies
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