Anyone have side effects to Cymbalta?

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Regular Member

Date Joined Dec 2010
Total Posts : 213
   Posted 12/22/2010 4:25 PM (GMT -6)   
I just saw my pain management doctor last Thursday and he changed one of my meds. I went from Celexa to Cymbalta. He also put me on a z-pack of antibiotics for bronchitis.

I have had some strange side effects. I feel very out of it, almost like I am numb. I have ringing in both of my ears. I also have had a few episodes. In one, I was standing with both arms above my head looking for something in the cupboard and my whole body started shaking uncontrollably and my legs started jerking like they were going to fail me. I was kind of frozen in the position for a minute or so and couldn't bring my arms down. My husband helped me and I managed to get my arms down and get sat down in a chair. In the other 2 episodes that I have had, my legs have just started jerking like they were going to give out and buckle and it took all of my strength to get to a chair and sit down instead of falling down.

Yes, I did call my docs office today. According to my docs office, they do not believe that this could possibly be a side effect of the cymbalta and I am supposed to keep taking it. The dose was originally started at 30mg twice a day. Once the side effects started, I lowered the dose to just one 30mg tablet once a day.

I am on several other medications, but in talking to the pharmacist on the phone today, they do not believe that the side effects are from the cymbalta or an interaction with any of my other meds. I have read online where a few people taking this drug have had side effects somewhat like this. As of right now, I am still taking it at 30mg per day as it is possible that my body may adjust to the medicine and the side effects may lessen.

My med list is: 30mg cymbalta 1 per day, 75mcg levothyroxine, gabapentin 300mg 3x a day, 30mg oxycodone dosage is 1/2 up to two tabs every 4 hours not to exceed 7 tabs per day, florinef .1mg 1 per day, bupropion (wellbutrin) 150mg per day, 40mg simvastatin 2 per day, magnesium supplement, multivitamin, calcium supplement, fish oil with omega 3 supplement. To be taken as needed, ambien 10mg for insomnia, promethazine (phenergan) 25mg for nausea, sumatriptan (imitrex) 50mg for migraines.

I just finished a z-pack of azithromycin (I believe it was 250mg pills), an antibiotic on Monday for bronchitis.

Boy, this post has turned into a book! Sorry about that! I also found out on Thursday that I now have a hernia on my left side. Not like I don't already have enough to deal with.

Has anyone else had these types of side effects taking cymbalta? Have you had any side effects taking cymbalta? Also, I posted my med list in case anyone would know if there is a contraindication in between any of my current meds with the cymbalta.


Regular Member

Date Joined Nov 2010
Total Posts : 104
   Posted 12/22/2010 5:09 PM (GMT -6)   
My boyfriend is on cymbalta and he's been waking up every morning at 4 am throwing up for the last 4 weeks..
“The most important things are the hardest things to say. They are the things you get ashamed of because words diminish your feelings - words shrink things that seem timeless when they are in your head to no more than living size when they are brought out.”

Regular Member

Date Joined Dec 2010
Total Posts : 226
   Posted 12/22/2010 7:02 PM (GMT -6)   
My mother is on cymbalta and the only real side effects I have noticed is if she misses a dose and then she has withdrawal symptoms: starts to cry over everything, nausious, and just out of it. I don't think she's ever had full jerking movements. We (or she really) haad major problems when it came to taking her gabapenton for neuropathy. It added problems instead of taking care of the throbbing in her legs. I personally don't believe it's neuropathy but it's like the last resort diagnosis because they have no clue what is causing the pain.

getting by
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Date Joined Sep 2007
Total Posts : 42612
   Posted 12/22/2010 7:28 PM (GMT -6)   
I have never taken cymbalta so I can't help you there. But I would definately contact the doctor again if this happens again. It is hard to say what is going on. It may be from the medication and may not. But I would keep an eye on this. This could be a case where cymbalta isn't the right medication for you. Take care. If you don't get satisfaction out of this doctor, do talk to another one. Listen to your body.

Hugs, Karen
  Moderator-Depression and fibromyalgia
fibromyalgia, Chronic fatigue, depression,allergies

Elite Member

Date Joined Apr 2007
Total Posts : 32602
   Posted 12/22/2010 7:33 PM (GMT -6)   
Hello and welcome to HealingWell.  I was on Cymbalta and had some unusual side effects that my Dr.  did not attribute to the medication.  I called Eli Lilly and Company, Indianapolis, Indiana 46285( the manufacturer of Cymbalta) and filed a formal concern.  My Dr. recieved a letter from the company asking her to explain my concerns.
I was weaned from Cymbalta and started on a new medication.
Hope this helps you in some small way.
Moderator: Anxiety/Panic, Osteoarthritis, GERD/Heartburn and Heart/Cardiovascular Disease.

"If you can't change the world, change your world"

Elite Member

Date Joined Mar 2009
Total Posts : 20282
   Posted 12/22/2010 10:13 PM (GMT -6)   
just weaned. weaning s/e are far worse than starting it--------------my view only. with healing compassion, jamie

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