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Reverse effects from effexor...

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Depression
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sk8
New Member
Joined : Jan 2005
Posts : 12
Posted 2/27/2005 3:49 PM (GMT -6)
My husband has been on paxil for years now but recently the doc suggested that he try effexor to get a "better bang for the buck!".  He took it for a month, initially with really no side effects.  Started on 37.5mg, then 2 weeks later 75mg, then 2 weeks later 150mg.  Over the last 1.5 weeks he has been getting increasingly frustrated, angry, depressed, even with suicidal thoughts and really short tempered.  We went to the doc and he said that he has never hear of these responses to effexor.  It was horrible, anything would set him off.  Yesterday we decided that maybe if we stopped the effexor that might help.  I'll tell you that within 36 hrs from taking his last dose of effexor he felt 75% better!

Does anyone else have similar experiences?

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Akram
Veteran Member
Joined : Feb 2005
Posts : 618
Posted 2/28/2005 12:46 AM (GMT -6)
certainly no simlar experience here with effexor, infact effexor worked very well for me. considering your husbend was for years on paxil maybe his body has gotten used to it, or let's say dependant on it. maybe effexor is just not for him or he might need an additional supliment medicine with effexor such as serqual or other mood stabilizers, wish your husbend the best..
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snohare
Veteran Member
Joined : Oct 2004
Posts : 2088
Posted 2/28/2005 1:03 AM (GMT -6)
Any SSRI (Selective Serotonin Re-uptake Inhibitor) may cause this sort of mood swing (emotional lability) and irritability. I don't know if Effexor is an SSRI, but you might find doing a search on "serotonin syndrome" may give you more pertinent information.

In my experience, any anti-depressant that doesn't work positively will work negatively, usually roller-coaster style, at least some of the time. But the SSRIs, particularly Prozac and Paxil, are notorious. skull

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Akram
Veteran Member
Joined : Feb 2005
Posts : 618
Posted 3/1/2005 2:22 AM (GMT -6)
you might find this intresting:

this document talks about certain cases with drug bad re-actions that happen from a genetic cause. i am sure its low number of cases that suffer from this

this is their main page, just becarefull about reading in here cause it could be full of junk who knows, but it is definantly an intresting read and maybe some usefull resources
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Jeannie143
Veteran Member
Joined : Apr 2004
Posts : 6065
Posted 3/1/2005 2:38 AM (GMT -6)
sk8,
I was on zoloft for years and have fibromyalgia. My dr. thought that I would have some pain relief as well as depression relief by switching to effexor... Within four days I was totally paranoid, thought the neighbors were watching me, accused my husband of drinking, (he'd been sober for 6 yrs.) and had an argument with my business partner... thought she had been embezzeling funds... I was a basket case! Called my doc and told her what was up and said "Can I just discontinue it?" She told me I might have problems with being dizzy... I"m like.. Duh! I'll take dizzy anyday over total paranoia!!! That stuff sure ain't for everybody!!! I'm back on my zoloft... I'll take some pain and my serenity anyday. (Darn drug companies! They are the ones pushing this stuff with your doctor!)
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Akram
Veteran Member
Joined : Feb 2005
Posts : 618
Posted 3/1/2005 2:44 AM (GMT -6)
wow jeannie.... i never had paranoia or such on that medicine. i guess thats why its important to keep working with your doctor closly to monitor any strange symptus etc when taking these drugs or stoping them... read the link i posted up there :)
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Ralph
Regular Member
Joined : Aug 2004
Posts : 139
Posted 3/1/2005 12:07 PM (GMT -6)
I don't want to judge any doctor on his or her motives, but I sometimes have felt like a bothersome, overactive, rambunctious, child being put in front of a TV set showing Shrek 2.

It seems very fashionable for GP's to get the old prescription pad out. "Next Patient please"

The Pharma giants keep churning these things out like the cars that saturate the marketplace.

This wasn't a rant, just comments
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Akram
Veteran Member
Joined : Feb 2005
Posts : 618
Posted 3/2/2005 4:40 AM (GMT -6)
Hrrmmm i am starting to think effexor could be the cause for my suspected anxiety attacks so , i'll take back what i said about not having any ubnormal side effects ! i read some other cases where this drug caused some anxiety in some patients and they switched to lexapro to fight off deppresion and it seemed to be better for them. but who knows ...
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