Anyone use Cymbalta for Depression

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BerryBlonde81
Regular Member


Date Joined Apr 2011
Total Posts : 157
   Posted 4/30/2011 1:09 PM (GMT -6)   
I am almost to start week 4 of Cymbalta, anyone have luck with this medication, and how long to take effect? Thanks!
Bipolar II - Second Opinion Diagnosed 4/11/2011

Medication History:
Zoloft 1996-2002?
Paxil 20mg 2002?-2001
Paxil 30mg 1/28/11-4/4/11 - increase not helpful; more anxiety; backed down to 20mg nightly
Switching Meds:
4/11/11 Paxil 20mg; Cymbalta 30mg nightly
4/18/11 Paxil 10mg; Cymbalta 60mg nightly
4/24/11 No Paxil; Cymbalta 60mg nightly
375mg daily Deptkote; .25-.5 Klonopin as need

getting by
Forum Moderator


Date Joined Sep 2007
Total Posts : 42608
   Posted 4/30/2011 3:06 PM (GMT -6)   
HI there,

I don't take cymbalta but there are others who have. As with any antidepressant, it takes a good six to eight weeks to reach it's full effect for you. But often you start feeling better sooner. Have you noticed any change in the way that you are feeling? Less moody or anything? It usually is a subtle change and happens gradually. So don't give up hope. Give it the full eight weeks before you make any decisions with it. One thing though, if you do decide to stop taking it, have your doctor help you wean off. I have heard the effects can be brutal. I hope that this medication works for you.

Do keep us posted.

Hugs, Karen
Moderator-Depression and fibromyalgia


fibromyalgia, Chronic fatigue, depression, allergies

BerryBlonde81
Regular Member


Date Joined Apr 2011
Total Posts : 157
   Posted 4/30/2011 9:06 PM (GMT -6)   
Hello, ending 3rd week on Cymbalta and the worse symptoms were nausea and fitfull sleep for a few days, I have been trying to take Klonopin in the evening so that I can have restful sleep. I will give this the full 8 weeks to reach full effect, I have noticed a little improvement, but nothing like I am looking for, I guess as long as I am not feeling like I am in a black hole, and not crying most of the day I have to be thankful? Also looking into a mood stabilizer for bipolar II as I keep hearing that I really need that to get my moods stabilized and looking for the best one to try for females, maybe Lamictal (or generic)? The small amount of Depakote that I have been on for a long time, does not really do anything I was always soo scared to increase the dose because it always increases my anxiety through the roof, with me thinking that the meds are doing harm to me! Fear of medication sucks, and I have would really like to be one that had trust in the meds and would let them do their job :( But I hear that bipolar is pretty much the hardest to treat acurately because the patients dont wanna take the meds! I just want to get better and want to feel alive again... :(
Bipolar II - Second Opinion Diagnosed 4/11/2011

Medication History:
Zoloft 1996-2002?
Paxil 20mg 2002?-2001
Paxil 30mg 1/28/11-4/4/11 - increase not helpful; more anxiety; backed down to 20mg nightly
Switching Meds:
4/11/11 Paxil 20mg; Cymbalta 30mg nightly
4/18/11 Paxil 10mg; Cymbalta 60mg nightly
4/24/11 No Paxil; Cymbalta 60mg nightly
375mg daily Deptkote; .25-.5 Klonopin as need

getting by
Forum Moderator


Date Joined Sep 2007
Total Posts : 42608
   Posted 4/30/2011 10:27 PM (GMT -6)   
I take abilify for a mood stabilizer and it works well for that. Plus it makes my antidepressant work better. It is expensive though. But sometimes they give me samples and that really helps me. Plus she writes the script for twice the milligram so that I can cut them into two pieces and that really helps. But there are many others that you could try.

You are right about bipolar people not wanting to take medications, but I thought that it had to do with the manic state. That a lot of people like to feel manic. They have energy and ambition to do things. Not always things that are good for them I have read though. I am sure that it is that much harder when you are bipolar on top of being depressed. I never was, but my sister is. She struggles with it a lot, but I think right now they have her on some pretty good meds. So that is good.

I hope that the cymbalta works well for you. This is going to be a slow change. So gradual that you don't really notice it until you are there. But you still could haev one of those moments where you wake up and realize that you feel good. I sure do hope that you do.

Keep posting, and we will be here for you. The weekends are kind of slow around here.

Hugs, Karen
Moderator-Depression and fibromyalgia


fibromyalgia, Chronic fatigue, depression, allergies

theHTreturns...
Elite Member


Date Joined Mar 2009
Total Posts : 20279
   Posted 5/1/2011 4:13 AM (GMT -6)   
having bi-polar 1 and depression is a bad mix!!!!!!!!!!!!!!!!!!!!!!!!! very difficult. this rapid-cycling mixed mood state sux, i for one do not enjoy it. cymbalta is a good med, jamie
SCHIZO-AFFECTIVE DISORDER, EMOTIONALLY UNSTABLE PERSONALITY DISORDER, BORDERLINE TYPE -AXIS 2 , BI-POLAR AFFECTIVE DISORDER AXIS 1

REMEMBER TO LOVE YOU. BE YOU AND BE TRUE.
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