I have never taken Deplin, but I think it is like a supplement. They either work or they don't. I believe that it is natural. I am not sure. But I too have read good reports on it, but everybody is different, and what works for some may not work for others.
I am happy that you have joined the forum and I wanted to welcome you. Keep posting, it is a little slow on the weekends, but picks up during the week. I hope that you are having a good day.
PS it seems to me that it doesn't work right away, it has to get into your system. Hopefully others will reply if I am wrong...
Moderator-Depression and fibromyalgia
fibromyalgia, Chronic fatigue, depression, allergies