I am not too familiar with sertaline, but a better mood over all is what I would expect. It is possible that it is starting to work early, and hopefully will get better. I think making things easy is good and then gradually get him back in the swing of regular life stress things, you know, everyday life. It isn't easy for some. But we have to face it as it happens.
I hope that you and your husband get on good. Hopefully somebody who is familiar with this medication can share with you what has worked for them and how it effected them.
I just looked it up and it is zoloft. It helped me, but gave me diarrhea. But for mood it was great. I hope it works for your husband.