Topamax and Pristiq Issues???

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KimInKY1212
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Date Joined Mar 2012
Total Posts : 2
   Posted 3/28/2012 12:07 PM (GMT -6)   
New to the site...

I've been taking Pristiq for a year and it's the best anit depressant I've found. Kicked the depression in 4 weeks!

Now my headaches are back after going 3 years without any major pain. Over the past month they have returned. My doc told me to take topamax for the headaches. I've had a reaction, serotonin reaction, to Lomotal (for IBS) and I'm worried that mixing the Pristiq with Topamax will cause problems. My doc said I should be fine.... sorry to say I'm not confident in her answer. She's been a great doc and always goes above to help me.

Just wondering if anyone else takes these two drugs together and if you've had any issues. Thanks!!!

getting by
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Date Joined Sep 2007
Total Posts : 42612
   Posted 3/28/2012 12:35 PM (GMT -6)   
I was going to start topomax once for weight loss. But started adderall instead. I would give it a try and see how it works. I am not sure about the serotonin in it. I will check it out.

Best wishes with the topomax and headaches.

Oh yes, welcome to the forum

Hugs, Karen
 
I don't see anything about serotonin in it.  But it says it is good for migraines and seizures.  Like I say, I would give it a try...  Listen to your doc...  Trust her...
Moderator-Depression and fibromyalgia


fibromyalgia, Chronic fatigue, depression, allergies

KimInKY1212
New Member


Date Joined Mar 2012
Total Posts : 2
   Posted 3/28/2012 8:44 PM (GMT -6)   
Thanks Karen,

I take Adderall XR 20mg twice daily for ADHD. It did take the pounds off, I had to remind myself to eat. I didn't even realize it was happening until my pants started to fall off at work one day while reaching to grab something off a shelf. Went from a size 10 to a 6 in 4 months. But... I took this med for my ADHD and it has been wonderful. I feel like the fog has been lifted! I feel normal for the 1st time in my life.

I also take Pristiq and it has been wonderful too. I've been on all kinds of anit depressants and after a yr they stop working. The combo of Pristiq and Adderall have been life changing for me. I feel great! I

I've suffered with cluster headaches and migraines for years, been to PT and TJM doc and nothing seems to get rid of the pain. I mean I can to the PT stretches and the pain is gone for an hour and then it comes back. Right now my doc has me taking hydrocodone for pain. Today she started me on topomax....

I've looked up drug reactions and it says Topomax and Adderall can cause major interactions with respiration and nervous system.

So, I asked the Pharm when I picked up my new script. They said I should be fine....

I love the "should"... really?????

So, I "should" live if I take them together? yeah, that's not convincing enough for me!

I guess I'm gonna hold off on starting it tonight and keep digging for answers.

Thanks for your input! I too was told I had fibro.... that sent me into the worst depression I've ever had. Just the news alone made me stop fighting for answers and happiness. I gave up. It wasn't until my husband went with me to an appt to learn more about fibro that I finally got it. He looked at the doc and said "she's a fighter, and I don't see her fighting anymore." He was right, I gave up! So I got back on the horse and pulled up my big girl panties and took myself to a shrink! 100mg of pristiq and then the adderall and poof.... no one fibro! Please don't misunderstand.... I believe fibro is real and it's terrible!!! It sucks all the life out of ya! I just couldn't allow myself to throw in the white flag and give up finding help. I hope you have a good doc on board and that you keep fighting to feel well! The med combo worked well for me, hope the adderoll helps with the fatigue! It also helped motivate me which helped me in every aspect of my life. Best of Luck!!!

getting by
Forum Moderator


Date Joined Sep 2007
Total Posts : 42612
   Posted 3/29/2012 6:16 AM (GMT -6)   
I understand about your fear of the topomax, but wouldn't you want to try it just to see if it takes away the headaches? I take a lot of the same meds as you too. NOt topomax though. It is up to you though and if you are reading about interactions, I understand your fears. But it would probably take the headaches away. Best wishes to you. I hope that you get this worked out. I will read too and see.

Hugs, Karen
Moderator-Depression and fibromyalgia


fibromyalgia, Chronic fatigue, depression, allergies
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