Seroquel for sleep

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Regular Member

Date Joined May 2009
Total Posts : 24
   Posted 4/22/2012 3:52 PM (GMT -6)   
I'm taking Seroquel for sleep but I have to keep upping the dose for it to work. Initially, I was on 12.5 mg/day, now my psychiatrist has me taking 31 mg/day. The problem is, it gives me really bad dry mouth. I've been taking 1% Pilocarpine which I use 5 drops mixed in 12 drops of water and swish it around in my mouth for 45 s 3X/day but that isn't working. Increasing the dose of Pilocarpine gives me a headache.

What's a good antipsychotic for sleep that is less likely to cause dry mouth? I don't want to take regular sleeping pills:

Veteran Member

Date Joined Jul 2009
Total Posts : 2042
   Posted 4/22/2012 11:27 PM (GMT -6)   
Have you tried Biotene products. They make toothpastes, mouth washes, sprays, gum, etc and it is designed to help people who suffer from dry mouth. It is an over the counter product so no script is needed.

Beyond that I don't really have any suggestion for you. This is something you would need to talk to your doctor about and then it would really come down to a trial and error thing. Most depression, anti anxiety, and anti psychotic meds can effect sleep and how the effect sleep really depends on the individual. They may make someone really tired while the same med can cause insomnia in someone else.
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Living Well
Veteran Member

Date Joined Feb 2011
Total Posts : 1276
   Posted 4/23/2012 5:06 AM (GMT -6)   
some people huge amounts of seroquel - up in the high hundreds - I'm on 50mg and my pdoc thinks thats a baby dose. Dry mouth is not okay - it can also cause dental issues. If you didn't want to see how you go at a higher dose (coz some symptoms go at higher doses) you could try Resitivit - it works a treat for me for sleep.

Regular Member

Date Joined May 2009
Total Posts : 24
   Posted 4/24/2012 11:07 PM (GMT -6)   
The Biotene products don't work for me. I buy the gel and hold it in my mouth because it's some relief, but as soon as the gel is completely swallowed, my dry mouth is as bad as before. No matter how many times I've tried this.

I'm on a high fluoride toothpaste because of the problems dry mouth can cause on your teeth.

What is Resitivit? Nothing came up when I Googled it.
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