I have heard of some people trying St. Johns Wort and have had very positive results from it. I did a lot of research on it, and learned a lot about
it. It is being used now for severe depression from an article I read. I shied away for years from antidepressants because of bad side effects - they were in the SSRI class family (such as Zoloft, Proxac, Lexapro, etc) and not only did I have really bad side effects, but they also numbed my emotions where I felt I was a zombie. I then tried SAM-e and was on it for three years and depression free. It is an Amino acid that is used for lifting mood and it supposed to be very safe and effective. You can get more info on at at the www SAM-e website. I took 400mg once a day about
45 minutes before a meal. Now, I am taking Remeron which is a tricyclic class of antidepressants and the only side effect I have had on it, is increased appetite, where I eat a bit more at meals. Other than that, I have had no side effects and it has worked great. Maybe the class of drugs were not right for you, and maybe a different class might be a bit better - I would check with your doctor. They also have the SSNRI's such as Cymbalta, and I think Effexor is another one.