Hello, my name is Monica, I was wondering if anyone knew about the early side effects of Zoloft. I'm taking 50 mg. for PMDD once a day, and had immediate results. I felt great but I was really tired so I started to take it at night. It's been two weeks now I don't know if it's still working, i have to admit I do feel better, though I'm going through ups and downs alot. Is this something I should be patient with and wait a month before talking with my doctor? Has anyone experienced something similiar?