I'm on Lamictal with Wellbutrin. It works very well for me.
Recently I started Pain Management and the doc switched me from Wellbutrin to Cymbalta to treat the newly diagnosed Fibromyalgia, and I guess was supposed to also take care of my depression and anxiety. When I noticed my depression getting worse, they immediately lowered the Cymbalta dose, and added back in the Wellbutrin at the same dose I was on before, but split out in 2 smaller doses per day.
Chronic Migraines, Bipolar II, Severe Depression, General Anxiety Disorder, Fibromyalgia, Osteoarthritis, Osteoporosis, Stage 3 Adrenal Insufficiency, Malabsorption, Hypoglycemic, Hyperparathyroidism, Hypothyroidism, Spine Issues: bulging & herniated discs, disc degeneration, bone spurs, whiplash, scoliosis + severe facet arthropathy & osteoporosis in lumbar. Extreme quick wit & humor. ;)