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Veteran Member

Date Joined Jun 2005
Total Posts : 527
   Posted 12/31/2005 10:44 PM (GMT -6)   
 Hi everyone & Happy New Year to all-- :-)       I sitting here, New Yrs Eve....looking for some real reassurance that I know I can get from the special good people here at HW.  
  I've already posted a similar post in the Bipolar section & received a very nice, caring response from Putter---but--i realized that I would probably get more responses on an anti-depressant on the "Depression" section.
  Here's the deal.    I've been diagnosed w major depression....& BP 2---pdoc  (who is very good, caring etc)---started me on Effexor XR 37.5 mg about 4 months ago (along w 75mg of Seroquel).   OK...in this time...depression has improved....my situation is getting better....but I have been getting effects from the Effexor that are bothersome...& ONE that is very upsetting!!!       Bothersome---wt. gain,constipation-gas-  BUT, more upsetting...feeling agitated...very bad dreams---waking up hyperventilating (which i have had for yrs....but upon awakening....my "anxiety" which usually "breaks" very quickly----stays with me.     Finally called up my pdoc Thurs.  Left message telling him this on his voice mail.   He called back next morning----I told him i wanted to discontinue Effexor.   He went along...kindly said--"OK, Robert----to wean off---take i capsule one day---none the next--do this for 10 days (5 doses)---then stop.   I was happy, then , remembering the "horror stories" i read on some sites about people coming off  Effexor--i asked.."Is that enough time?  Just 10 days...5 doses?"   He calmly responded.."Yes, Rob--you are on the lowest dose & you should be OK."      We have a Jan 10 appt anyway.
   My question to all of you dear people here at HW.  I've been doing searches on "weaning off of Effexor"---& I get nothing but "horror tales"...Brain Zaps...agitation....nightmares....dizziness...nausea....hostility---You get the idea!!!   My wife (who has been so supportive of me)--says I read too much of these sites.      I even called my pharmacist Fri----he said, not to worry.   But...when I read all these "horror stories" online...it's like I'm waiting for the axe to fall on me.
   Are there ANY people here...who have been on Effexor....bigger doses than me...longer than me...& who have discontinued...WITHOUT any horror tales???      Also---do you feel my pdocs...."weaning" schedule...is long enough??   PLEASE...someone....anyone get back....with something positive......& supportive, so my fears can be lessened.  These darn posts just scare people!     Thanks to everyone---Blessings---Robert :-)

Veteran Member

Date Joined Oct 2005
Total Posts : 540
   Posted 1/2/2006 10:13 PM (GMT -6)   

Hi Wotan!

Have no  fear! I am one peson who was on 225 ml of effexor about 2 yrs ago and went off due to the sexual side effects, and I had no problems at all.  I can't quite remember how  quickly I went off, but I don't remember any troubles.  I am on it again, right now at 75 mg, and will   probably be going up a bit at my next dr appointment.

I hope it will go as easily for you as it did for me! tongue



dx: fibromyalgia, IBS-C,Myofacial Pain Syndrome, Chronic Headaches, hypothyroidism,anemia, insomnia,mild depression.
rx: Effexor, clonazapam, baclofen,Tylenol#3,iron pills,synthroid
supplements: probiotics, garlic pills, magnesium, melatonin, b12(sublingual)
Jerrimiah 29:11

Regular Member

Date Joined Nov 2005
Total Posts : 30
   Posted 1/4/2006 2:21 PM (GMT -6)   
Same here, Wotan,
I was on 225 mg it took me about 4 weeks to kick it all, and another week or two for the brain shivers to disappear.
I have also heard stories. If you can get on the stuff, than you are tough enough to get off. You are on a low dose it it won't make you sick.
Have at it, man!!
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