Posted 7/7/2018 12:49 PM (GMT -6)
My GERD and LES insufficiency began a decade before starting Venlafaxine. I blamed it on Naproxen, but it could have been just normal aging. No one ever knows these things. I do know that GI distress is the most common SE from Effexor, but if you are taking the ER/XR form and taking it with food and able to sit upright after taking it, then it should not be a problem. I'd had Barrett's esophagus long before starting any A/D and things like onions cause more problems than does the 150mg/day of Effexor.
Changing to a different drug MAY improve your condition for now, but I suspect you'll be experiencing it a lot more in the future.