You may need to bump up your dose of Wellbutrin to 300mg per day, that is what I am on and have been for years. I have looked into other ways to increase dopamine and the only one that is reliable is exercise. I am also on an SNRI, which works better for me than an SSRI - I think they have a little dopamine effect, also. I find the whole dopamine issue interesting, as my brother has early onset Parkinson's, which is also a dopamine disorder.
Thanks for the reply.
You said you are on 300mg daily for years, that is scary. Why would one need such high dose for years?
I have depression/major depressive disorder for the last 5 years. Undiagnosed and untreated. I just started the treatment 3 weeks back. Also taking SNRI for serotonin and norepinephrine. My mood is good, and subtle improvement in norepinephrine memory attention sharpness.
My arousals and desires, engagement in desires, deriving pleasures those functionalities are dead. That is the main problem.
I guess depression of many years changes/lowers the receptors in the brain. Taking Tyrosine and other supplements does not help. Bupropion is a receptor agonist, I wonder how long it takes to restore normal receptor density and activity. What do you think of this?