Hi Bear, It is nice to see you over here
. Yes, antidepressants over time can build up in our bodies and start to become less effective. It all depends on the medication, dosage and of course your own personal chemical system. If this started for no apparent reason then perhaps you may want to give your doc a call to see about
an adjustment in your dosage. Most times this does help to level you off and prevent another major depressive episode.