Prozac & Wellbutrin

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Regular Member

Date Joined May 2006
Total Posts : 115
   Posted 11/8/2006 9:53 AM (GMT -6)   
I've been taking prozac 40mg per day for about 3 weeks now, saw doc for follow up yesterday and she wants to add 100mg of wellbutrin. She thinks a combination will be better rather than just increasing the prozac. I'm nervous about taking two anti-d's. What do any of you think, is this common?

Regular Member

Date Joined Oct 2006
Total Posts : 20
   Posted 11/8/2006 11:12 AM (GMT -6)   
At one point, I was taking 4 antidepressants. I have taken Wellbutrin XL 450 mg. in the past & it was a good antidepressant. Sometimes, an "antidepressant cocktail" is prescribed because each antidepressant works on different aspects of the brain chemistry (mood, cognition & behavior). For example, Wellbutrin primarily works with Dopamine which helps with attention, motivation, pleasure & reward. I received this information from my old Psychiatrist & it is a handout which discusses the insights on neurotransmitters. At any rate, it is common to take more than 1 antidepressant.

Take Care.
DX: Clinical Depression 12/95 & Bi-Polar Disorder 10/03

RX: Stopped Antidepressants 08/06 & Metformin ER 1500 mg. (Fertility)

Post Edited (indygirl) : 11/8/2006 9:39:40 AM (GMT-7)

Regular Member

Date Joined May 2006
Total Posts : 115
   Posted 11/8/2006 11:59 AM (GMT -6)   
Thank you very much! This is still all new to me so the info is helpful.
Thanks again.

Veteran Member

Date Joined Oct 2006
Total Posts : 902
   Posted 11/9/2006 1:19 AM (GMT -6)   
Hi Kath, I too am taking 2 anti-depressants. I always got my meds from my regular family doctor but after suffering major loss/grief/PTSD I had an emotional breakdown. Eventually, I went to a psychiatrist and she put me on Lexapro (SSRI) and Wellbutrin. I'm on low doses of both but it did help me. Take care.
DX: chronic migraine, cervical degeneration, depression/anxiety 
RX: Wellbutrin, Lexapro, Soma, Immitrex 
"You don't find out that God is all you've got until God is all you've got."

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