Zoloft and weight gain

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New Member

Date Joined Jan 2007
Total Posts : 2
   Posted 1/30/2007 10:18 PM (GMT -6)   
mad  I started taking Zoloft about one year ago. At first I thought the drug was great and it helped me with my OCD. Soon after I began to notice that my clothes were tighter. I have gained 25lbs. The weight gain has been around my stomach and waist which is the first for me. I had been and continue to work out with a personal trainer twice a week with weights and four days a week I do cardio for 30-45 minutes each day. I have been off Zoloft for about two weeks now and I have not lost any weight. I know it has not been that long but any weight loss at this point would be great. I am looking for ideas and suggestions as to what I am doing wrong or what I need to do. The lastest effort from my trainer is a daily journal of what I eat.

Regular Member

Date Joined Jan 2007
Total Posts : 184
   Posted 1/31/2007 8:22 AM (GMT -6)   
Unfortunately, the SSRIs often cause weight gain over time, with Paxil generally being the worst, but they can all do it. I've taken Zoloft for 6 years and gained weight, but not as bad as Paxil.

I think working with a trainer and watching what you eat is a great step. Sometimes you have to accept trade-offs to stay well.

New Member

Date Joined Jan 2007
Total Posts : 2
   Posted 1/31/2007 7:17 PM (GMT -6)   
Thanks for taking the time to respond and for the information. I really appreciate your time. My main hope is that my weight issues and the number on the scale does not trigger my OSD symptoms. Thanks again for your response.

Regular Member

Date Joined Oct 2005
Total Posts : 94
   Posted 2/20/2007 3:33 PM (GMT -6)   

Welcome to the forum. There are quite a few of us who have experienced exactly what you have experienced...a large weight gain while on Zoloft.

I've personally had a very large weight gain over the last 6 years. The Zoloft is great for my OCD but heck on my body. It's frustrating and I've spent many a night crying about it.

Then I read something somewhere. An author asked "If I am fat, is that the worst thing in the world I can be? Is it worse than being a liar or a cheat or a thief or something equally as bad?" That got me to thinking...My OCD is under control, I function like my old self and I carry around extra weight. While I'm still not happy about it and still feel bad about it sometimes, other times I remind myself of those questions...Is this the worse thing I can be?

Hang in there...There is support on this site. We just all have to come together and demand that the drug companies do more research and come up with a better alternative.

New Member

Date Joined Nov 2006
Total Posts : 13
   Posted 2/28/2007 9:49 PM (GMT -6)   
Good seeing you're still here snickersmom!!!  Those are some very wise words you have!!  I'm still fat and sassy but I'm gonna work on that some time!!!  At least I'm in a good mood about it! cool cool I'm sending love to all of you! Robindodie

New Member

Date Joined Mar 2007
Total Posts : 1
   Posted 3/12/2007 1:59 AM (GMT -6)   
I started taking Zoloft about 7 months ago after the birth of my son for anxiety. I lost all the weight i gained while pregnant (40)lbs before i started the Zoloft. I have know gained all 40 lbs back. I have talked to my Dr. but he keeps telling me the weight gain isnt from the Zoloft any ideas on what i can do. Or how i can get the Dr. to beleive it is from the Zoloft. Any help would be great thanks
Vasula :)

Post Edited (Vasula) : 3/12/2007 1:06:49 AM (GMT-6)

Veteran Member

Date Joined Dec 2005
Total Posts : 3036
   Posted 3/12/2007 7:09 AM (GMT -6)   
Hi Vasula,
If your doctor is not listening to you,then I would just tell him that you want a different med. Simple as that.
You pay them to help you. So,if you are not comfortable with what you are taking,then get on the phone and call him.
It frustrates me when some doctors do not listen.

Good luck

Mod- Depression

Chronic Depression, Panic Attacks,Anxiety Attacks,Anorexia


"I am woman,hear me roar one day and cry the next!!!"

New Member

Date Joined Feb 2007
Total Posts : 5
   Posted 3/13/2007 2:52 AM (GMT -6)   
Been on zoloft for almost a year. Most certainly gained weight. about 15 pounds. I was on a diet awhile back. I worked my butt off. I was a cardio maniac. I was doing strength training. I was totally eating healthy and watching what I ate at night, etc. Didn't have anything really to show for it. I've been on diets before Zoloft and I lost weight with effort but ease compared to now where it feels impossible. I'm getting on Zoloft very slowly and hoping to continue trying my best.

Regular Member

Date Joined Feb 2007
Total Posts : 138
   Posted 3/13/2007 9:25 AM (GMT -6)   
I took both Paxil and Zoloft - at different times. Paxil made me so sleepy - slept about 14 hours a day. So, yeah, I gained weight - about 30 lbs. Zoloft also made me gain. When it was all said and done I had gained about 40 lbs.

Undiagnosed symptoms for many years. Dx in 12/06. Sm. Bowel resection (60cm.) 1/07
currently on 50 mg. Imuran, 40 mg. pred., vicodin for continuing pain

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