Lexapro and weight gain and exhaustion

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New Member

Date Joined Oct 2006
Total Posts : 3
   Posted 2/13/2007 12:58 PM (GMT -6)   
Hello everyone, I have been on lexapro couple of month now and I feel so much better.
I have two concerns though
One I can't stop eating, I'm never full I just always feel like I want to eat or snack on something and its causing me weight gain. Does anyone knows howto fix this issue. I was going to order some phentramine online but I'm scared of thw two drugs mixed together. Also I take it at night because if I take in the morning I get very tired all day. But next day in the morning I can't even wake up I feel like sleeping all the time.
Any suggestion should I consider switching to something else.
Thanks for all your feedback.

Regular Member

Date Joined Jan 2007
Total Posts : 184
   Posted 2/13/2007 4:55 PM (GMT -6)   
Sometimes the eating is simply your body recovering from the depression and loss of weight that goes with it. You feel better now and are able to enjoy food again. Other times, it is the medication causing a side effect.

Lexapro is becoming notorious for Paxil-like side effects of tiredness, weight gain and apathy. This may be due to the fact it is relatively selective for serotonin and is a very powerful inhibitor, which can cause various downregulation of other neurotransmitters to compensate.

Paxil was the worst for me, while Zoloft was the best. But everyone is different. I would give the Lexapro at least six to nine months, and if you still feel better, discuss your options with the doctor.

Let us know how you do!

Regular Member

Date Joined Feb 2007
Total Posts : 22
   Posted 2/13/2007 11:02 PM (GMT -6)   
Hi, Amira--
I was on Lexapro for about 2 years. I felt ravenous for the first few months, but I think it may simply have been that I'd had no appetite before. Lexapro did make me crave sweets, though....I may be the one woman on Earth who doesn't like chocolate. No interest in ice cream, cake or cookies. I prefer sour stuff like pickles. But once I started Lexapro, I could eat a bathtub of Jelly Bellys and it still wouldn't be enough. I could also drink what felt like gallons of booze. My chemistry must have had an opening there... I eventually found that baby carrots and hummus or cherry tomatoes in kosher salt were healthier substitutes. I also mixed therapies and did a baked potato w/sour cream before bed a la "Potatoes Not Prozac." PNP suggests that sugar sensitivity and rapid serotonin depletion may correlate. Yet I only crave carbs and sugars when I'm on SSRIs! This may have something to do with the selectivity that Geebs pointed out.
I hear you on the dosage timing, too. I fiddled around with times and ended up taking it about 3 hours before I thought I was going to go to bed. This worked best for me-- even if my bedtime wasn't consistent, I usually had to get up at the same time each day, and this timing worked.
I'm just returning to meds after a year off. I couldn't even think lately-- just wanted to sleep all the time. My p-doc prescribed Cymbalta, which includes a norepinephrine reuptake inhibitor, so we'll see if I become the Jelly Belly bandit again.
Really glad to hear you're feeling better. Hope to hear from you again soon.

Regular Member

Date Joined Jan 2007
Total Posts : 184
   Posted 2/14/2007 8:36 AM (GMT -6)   
The same thing happened to me when I first took Paxil. Once I recovered from the depression, I started eating more and really enjoying my food. But after about six months I was eating sweets like there was no tomorrow, including cakes, cookies, pies...you name it! And I never was much of a sweet tooth!
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