I take high doses of my meds. My system is really resistant to medication, and because of my gastric bypass, absorbsion is an issue. My Klonopin dose is 4mg am/4mg pm. My Buspar dosage is 15mg am/15mg pm. I've been on these kind of meds for probably eight years. I think I've tried just about everything, but never have really found the right combination of meds that actually make me feel better.
My biggest problem is that I am very resistant to pain meds, as several have little or no affect on me, like Demoral and Morphine. Heck, even the dentist has to use some kind of "super" novacaine, and usually has to numb me up four times before he can start working on me. It usually takes at least an hours before he can actually do anything to my teeth.
I still have anxiety frequently, for no apparent reason, and the occasional panic attack out of the blue. My panic attacks hit on some weird delay system, and they occur at totally stupid times. For instance, I'll get a panic attack going up the stairs. Can't go up, can't go down. I'll just sit there feeling really stupid, but not able to do anything about it. After a few minutes, it goes away and I'm back to normal. There are activities that I know will set off major anxiety or give me an outright panic attack. The worst thing for me is trying to pick out a picture frame if there are too many options. Having to take a shower does it. Going into a store without knowing specific items I need to get. Just stupid stuff.
I also take Wellbutrin 300mg and Lexapro 15mg per day for depression, and 200mg of Trazadone at bedtime to sleep.
Even with taking all this stuff, I still feel like I'm in a hole most of the time. I always feel stressed out, even if I don't have anything I have to do. The list of stuff I need to do is so long, I don't know where to start. I usually just end up on my computer or watching TV or DVDs.
Good luck and let us know how you are doing.