Does anyone take more than 60mgs of Cymbalta?

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Date Joined Nov 2003
Total Posts : 7314
   Posted 7/9/2007 7:19 PM (GMT -6)   
Hello everyone. I spend most of my time of the Crohn's and Chronic Pain Forums, but I also suffer from Depression. I've also got Ankylosing Spondylitis, a form of autoimmune, inflammatory arthritis. This has affectedd almost all of my joints and causes a great deal of pain.
about 18 months ago, I switched from Paxil to Cymbalta, hoping to get some additional relief from the nerve pain and the depression. I had done very well on Paxil, but after I was forced to stop working, it just wasn't enough anymore.
Cymbalta has worked very well for me so far, but I still battle both the depression and pain on a daily basis. On Friday, I had a follow up appt with my Promary Doc. He told me that the Drug Reps are now reporting that people who respond well to Cymbalta, but could use additional relief are now being titrated up to as much as 120 mgs. Since I fall into that catagory, he gave me a script for 30mg caps to add to my 60mgs. If I tolerate this well, we'll discuss going up to 120mgs later.
Since I have an inate need to research every med I take, I came home and began looking for info about the higher dosages of Cymbalta. All I can find are references in the Prescribing Information which state that dosages above 60mgs did ot produce better results. Now I'm confused, so I was hoping to find anyone else on one of these higher doses too.
Thanks for taking the time to read my novel. I hope you all are having a good evening. Be well.

Keah a.k.a. Wormy
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Post Edited (Keah) : 7/9/2007 7:00:36 PM (GMT-6)

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Date Joined Jan 2006
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   Posted 7/10/2007 5:11 AM (GMT -6)   

As far as I was aware, 60mgs was the max dose but Im not a doctor. I cant say that I remember seeing anyone taking a higher dose, but my memory comes and goes so I could be wrong! Let us know how you get on!


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Date Joined Apr 2007
Total Posts : 32602
   Posted 7/10/2007 4:10 PM (GMT -6)   

Hey Keah

Kitt here.  You can quit looking for info on the internet.........My Pdoc has information that cymbalta initial dosing was to low and I am at the 120mg dose.

Yes it is working.  I have not had a bad spell in a long time now, I think we went to the 120mg back in February.

Before that we tried many ADs without success.  I do not spend my days in tears and wondering what is going to happen to me. When Dr.  wanted to  increase dose, I thought why not. I was not getting better.

I have also worked through therapy.

I don't notice any side effects in the increased dose but I got better.

Bless you.


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Date Joined Nov 2003
Total Posts : 7314
   Posted 7/10/2007 4:58 PM (GMT -6)   
Thanks Kitt. I'm glad that it's working for you. I just started on 90mgs and woke up th next day (yesterday) with a killer migraine. It's still lingering today and I'm hoping like heck that this isn't an adverse reaction to the increased dose. I've had migraines for 39 years, but I've learned that sometimes they can be related to allergies and even meds. I guess I'll have to stick it out a little longer and see what happens.

Thanks again & Be well.
Keah a.k.a. Wormy
 God helps those who help themselves.
Please help us support this invaluable forum.
Crohn's Forum Moderator

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