Hi Susie:) I am on pred. What other meds are you on? It doesn't make me go high anymore with care but I am going low like you at night and at fasting check. I think it is my diabetic meds and am reducing them slowly at night. If this keeps up, call your doctor soon. Testing machines can be off on the numbers and you may be lower than you think. Too easy to get into trouble with low blood sugars. The pred can cause the shaking especially if you are new too it or on high doses. The first time I was on it, I shook day and night. It was just miserable. Remember, when in doubt, check with a medical professional. Take care.