nice to hear from you again.Isn't it an obvious fact that tight glycemic control delays or prevents complications!It goes without saying!
I quote"According to a meta-analysis (144) of five studies including a total of 108 patients, dietary protein restriction slowed the progression of diabetic nephropathy in patients with type 1 diabetes. More recently, a 4-year randomized controlled trial in 82 patients with type 1 diabetes with progressive diabetic nephropathy showed that a moderately low–protein diet (0.9 g · kg–1 · day–1) reduced the risk of end-stage renal disease or death by 76%, although no effect on GFR decline was observed (145). The mechanisms by which a low-protein diet may reduce progression of diabetic nephropathy are still unknown, but might be related to improved lipid profile and/or glomerular hemodynamics"
The link is given below.Though the article is long,it makes interesting reading.
I again quote from the same article"Diabetic nephropathy develops in, at most, 40% of patients with diabetes, even when high glucose levels are maintained for long periods of time. This observation raised the concept that a subset of patients have an increased susceptibility to diabetic nephropathy. Furthermore, epidemiological (42) and familial studies (43–47) have demonstrated that genetic susceptibility contributes to the development of diabetic nephropathy in patients with both type 1 and type 2 diabetes.The main potentially modifiable diabetic nephropathy initiation and progression factors in susceptible individuals are sustained hyperglycemia (17,18,48,49) and hypertension (50–52). Other putative risk factors are glomerular hyperfiltration (53–55), smoking (56,57), dyslipidemia (18,50,58,59), proteinuria levels (60,61), and dietary factors, such as the amount and source of protein (62–64) and fat (65) in the diet".
Post Edited (spooky) : 8/22/2006 6:25:58 PM (GMT-6)