Drug to prevent type 2 diabetes...(treats impaired glucose regulation)

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Regular Member

Date Joined Oct 2005
Total Posts : 242
   Posted 9/15/2006 8:10 AM (GMT -7)   
Hi Everyone,
Just thought this article was quite interesting.
Claire x

Veteran Member

Date Joined Oct 2005
Total Posts : 534
   Posted 9/19/2006 11:10 AM (GMT -7)   

Hi Claire,

The article you posted talks about rosiglitazone (AVANDIA).  This belongs to the class of drugs called thiazolidinediones.  The other major drug in this class is ACTOS.  In very simple terms, what these drugs do is increase a persons sensitivity to insulin by attaching to the insulin receptors throughout a persons body and INCREASING the sensitivity to insulin in the bloodstream, thus allowing more sugar to be removed. 

The side effect most normally observed is "swelling" of the legs or arms due to fluid retention.  This is really dangerous for heart patients.  But aside from this there is a real potential for liver damage.  The link for this is tenuous but most endocrinologists will make you have a liver panel every 30 days while using the drug.  With these two side effects, I'd be hard pressed to say ANYONE should take this drug as a PREVENTATIVE. I was taking this drug for about a year and when I started taking Byetta it was the first oral med my doctor got rid of! (and yes, I suffered from the fluid retention. Complained about it and my doctor said, would you rather have fluid retention or high blood sugar. Grrrrrrr!)

In any event, this drug has been around for awhile and I would think twice before using it for anything but really uncontrolled type 2 diabetes.

scool Warren

New Member

Date Joined Sep 2006
Total Posts : 10
   Posted 9/19/2006 7:37 PM (GMT -7)   

Wish I knew how to make this a 'live' link, but anyway! Look at what I found just today!
[I think I fixed it, Chump. Just learned how. I just put a <> around it.]

Post Edited By Moderator (eljay1066) : 9/19/2006 8:53:13 PM (GMT-6)

Veteran Member

Date Joined Apr 2004
Total Posts : 6056
   Posted 9/19/2006 8:36 PM (GMT -7)   

I have been using advandia with no problems for many years. I've had my liver tests and am now down to twice a year for those. I have no swelling. I would recommend this med to anyone trying to get their sugars under control as long as they do their homework and stay on top of their symptoms. This med has worked very well for me in conjunction with metformin and Lantus insulin.
~ Jeannie

"People are like stained glass windows: They sparkle and shine when the sun's out, but when the darkness sets in, their true beauty is revealed only if there is light within."

- Elizabeth Kubler-Ross

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