depakote reaction?

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Beth B. in TN
Regular Member

Date Joined Oct 2005
Total Posts : 83
   Posted 10/22/2006 6:10 PM (GMT -7)   
Okay long story...Kimmy had a bad month over a month ago. first a status with diastat and ride to E.R. on 9-5 then a status/cluster about5 days later and amitted to give ativan and watch. Then, another status at school and admitted to start depakote I.V. and take her off of zonegran cold. Then a week later..throwing up so much she started vomiting blood, just a vein in the esophagus from throwing up so much...So the nuero, lowered the depakote to see if that was the problem...she stopped throwing up. So he added some topamax to give some extra support since the depakote had stopped the seizure but now he was lowering it....So, now she was on trileptal 900mg 2x a day, lamictal 75 mg 2x day, topamax 50 mg 2 x a day, and deakote ER 1000 mg at night....Well, she went amonth doing great and then she had a cluster last Wed. (now I know this may sound weird but Kimmy seems to have problems with overcast days and I was happy because it had been overcast all week and she didn't have one...then Wed afternoon...a cluster.So, now he was hoping she was "used" to the depakote, so he upped it back to 1500mg, Well guess who just started throwing up again all this evening....Any advice? Anybody ever have problems with overcast days? Concerned mom to 16 year old Kimmy partail complex with sometimes secondary generalization.
Beth B. in TN

Regular Member

Date Joined Nov 2004
Total Posts : 167
   Posted 10/25/2006 1:05 AM (GMT -7)   
Hi Beth,

Overcast days can effect our moods and our moods can have some effect on our seizure thresholds. I'm not a neruo by any means. This is just my personal experience. It sounds like Kimmy is having a rough time finding a combination of meds that works for her. Many of us have gone through very tough and trying times this way. My thoughts go out to both of you. My best suggestion is to keep an open line of communication with her neuro. That is the quickest and easiest way to find the right combination and dosage for Kimmy.
Intractible Epilepsy,7 knee surgeries, 1 shoulder surgery, compressed discs in spine, Curvature of spine, sacroiliac joint disfunction, leg length deficency. Meds:  Topamax 300mg's, Klonopin 1.5mg's, Lamictal 200 mg's
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