Hey, so I've been reading some of the threads and I've bumped into a lot of theories on causes. I'm a bit skeptical of some of the theories out there. I'm wondering if theres people on here that have gone with the sleep idea like me and have anything to add to this...
I'm personally of the belief that fibro stems from sleep issues. I've thought this for years because it just made sense with all the research I've done over the years. Recently, my dentist actually wanted me to get a sleep study done because he thought I was grinding my teeth in my sleep. I told him I didn't. Well, I had the sleep study done this past August. The Sleep Tech was able to tell me I didn't grind my teeth, have sleep apnea or any of the other common sleep problems. I told him I could've told him that myself. Then I had the follow up. Guess what? The doc confirmed the guess I've had for years: delta wave sleep interruption. I got talking to him about
this and it's relation to fibro. He said that most of his patients have the more common sleep issues. He said every once in a while he'll get a patient like me and that most of them have already been diagnosed with fibro or a lot of their symptoms fit fibro.
Growth hormone, which repairs muscles, is released during delta wave sleep, which could account for the muscle pain. Studies with rats have shown that sleep deprivation techniques, where they're not allowed to reach delta-wave sleep, reduces neuroplasticity in their brains: thus resulting in poor learning and memory abilities (fibro fog). And, of course, if you're not getting delta-wave sleep (restorative sleep), you're going to feel fatigued.
As for why the delta-wave sleep interruption happens? I don't know. Although I haven't spent that much time looking into it, I think scientists don't quite understand what regulates sleep cycles, yet. I do know serotonin is involved in the circadian rhythm (onset of sleepiness, length of sleep, length of wakefulness).
1) Has anyone else here been diagnosed with delta-wave sleep interruption?
2) Is anyone here on Xyrem? It's also know as sodium oxybate, gamma-hydroxybutyric acid or GHB. It's one of the few chemicals thats listed on two US drug schedules. It's street form, GHB ("date-rape drug"), is Schedule I, thus illegal. However, Jazz Pharmaceuticals, produces it under Xyrem and is FDA approved for narcolepsy. Theres some studies out there that suggests it promotes delta wave sleep. It's in clinical trials for fibromyalgia.
Pre-Pharmacy Student. Retail Pharm Tech. Fibromyalgia.
MuseKill: the name I came up with for a personal domain when I was 15. At 21, I have no clue what it means. It's just my online pseudonym.
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Post Edited (musekill) : 12/5/2008 1:48:10 PM (GMT-7)