Cymbalta anyone??

New Topic Post Reply Printable Version
[ << Previous Thread | Next Thread >> ]

Regular Member

Date Joined May 2008
Total Posts : 59
   Posted 1/26/2009 7:10 AM (GMT -7)   
Anyone have any experience (good or bad) with Cymbalta?

My DR gave me samples and wants me to start taking 30mg for 3 days and then up it to 60mg a day.

Side effects?

Any info would be greatly appreciated. I have read some stuff on this med and now I am scared to take it.


PS: I am no longer taking the Ultram so I can take the Cymbalta (I guess you are not supposed to take both together).
Fibromyalgia, Endometriosis, Pelvic adhesions, IBS, Asthma, Anxiety, Slipped discs, Irritable bladder, High Blood Pressure, and GERD. 
Lyrica 150mg (3X a day), Ambien 10mg, Tramadol ER 300mg, Aspirin 325mg (as needed for headaches), still in pain.

Post Edited (Mominmich2) : 1/26/2009 7:14:02 AM (GMT-7)

Veteran Member

Date Joined Aug 2007
Total Posts : 6067
   Posted 1/26/2009 8:23 AM (GMT -7)   
I'm in the same boat you are. I was suppose to start taking it months ago and still haven't. I read positive things and think I should try it but then read something negative and decide not to. I do have a med phobia and hate taking new meds so my rheumy told me to open a capsule and try a little at a time but with all that has been going on in my life I haven't even done that. It could be just what I need but I won't know unless I try it.
Good luck.
luv and hugs
Forum Moderator Fibromyalgia
Fibro,Sjogrens, Anxiety, Gastroparesis, IBS, Gastritis, Allergies, High Blood Pressure, Low Blood Sodium and Osteoarthritis
Amitriptyline, Celexa, Xanax, Synthroid, Zyrtec, Micardis, Spironalactone, Tylenol, Reglan, Lidoderm Patches and Tramadol
Co Q 10, Super B Complex, Extra B12, Multi vitamin

New Member

Date Joined Jan 2009
Total Posts : 1
   Posted 1/26/2009 8:55 AM (GMT -7)   
I have been prescribed Cymbalta and the low (regular) dose only worked for a short time. When my doctor upped the dose (doubled it), I started having increased problems with neuropathy in my arms and legs.... plus, I stay in a state of deep depression and the Cymbalta doesn't really seem to have any affect on that at all.

dave z
Regular Member

Date Joined Dec 2004
Total Posts : 164
   Posted 1/26/2009 9:13 AM (GMT -7)   
Hi mominmich2   I have bumped up (was admitted to the hospital because of cymbalta) thred.  You can find it in the depression forum.  It has very good information about cymbalta. 

Regular Member

Date Joined Jan 2009
Total Posts : 73
   Posted 1/26/2009 10:59 AM (GMT -7)   
I also have a bad med phobia, have never tried cymbalta before...
Sorry I can't be of help.
21 years old
Fibromyalgia, Bipolar, OCD, Dependent Personality Disorder
"You can't be brave if you've only had wonderful things happen to you." -Mary Tyler Moore

Regular Member

Date Joined Jul 2008
Total Posts : 48
   Posted 1/26/2009 7:01 PM (GMT -7)   
I tried Cymbalta (15 mg. for 3 days, 30 mg. for 1 week, then increased to 60 mg. 2 weeks later) and it helped with pain but it made me extremely tired. My doc also forewarned me of the side effects when I started and said I would have nausea for up to 2 weeks at first but it would subside. We played around with it for a while and decreased to 30mg. because I really wanted to be able to stay on it and we added Phentermine for energy. I had more energy during the day and lost weight but I was so tired by about 4:00 every day, then I couldn't sleep at night. (I know, crazy right?). My doc then decided I should take 20 mg at night every other night and take an ambien with it. This also did not work because the ambien made me tired the next day. I stopped taking the ambien and that seemed to keep me from getting too tired. The only problem with this was that the Cymbalta really didn't have any effect since I couldn't even take a clinical dose. I also had a psych. evaluation during this time and found out that I was severely depressed despite being on the Cymbalta. I am off of it now and didn't experience any withdrawal but I was barely taking it by the end so I guess I was weaned off. I guess my point is that us fibromites can't seem to take any new med with the assumption that we know the outcome (even from each other's experiences). I hope this helped, I know it was kind of long-winded!

Regular Member

Date Joined Jul 2008
Total Posts : 48
   Posted 1/26/2009 7:07 PM (GMT -7)   
Oh, I forgot to tell you that I read something recently about starting new meds on people with FM and it said our initial doses should be only 10% of the typical beginning dose. This totally makes sense to me since I just spent a week in Wellbutrin Hell! Obviously we just cannot handle even the smallest doses of certain meds.

Veteran Member

Date Joined Jun 2008
Total Posts : 844
   Posted 1/26/2009 8:28 PM (GMT -7)   

I've been on Cymbalta for three months and love it.  It has given me more energy and curbed my appetite even though I haven't lost any weight.  I'm also taking Lyrica in a small dose, because I'm afraid of it causing me to gain weight.  They have both been great for me and I also take Flexeril at bedtime and I'm sleeping so much better.  The only thing is I'm still sleepy when the clock goes off.  When I get up and get going though I don't feel a bit drug down. 

My only problem is all of them together are causing me to stay constipated and I have to take otc vegetable laxative every night. 

I feel so much better since my rheumy put me on them, but I'm so afraid of the side effects and long term use.  I have been thinking about getting off them all and seeing how I feel then.

I hate taking any kind of meds and these are powerful ones so I'll let you know what I decide.

In meantime give Cymbalta a try.  You can always get off of it if you don't like the feeling it gives you.

God Bless!





Of all the things that I have lost, I miss my mind the most!!!!

Regular Member

Date Joined Nov 2007
Total Posts : 130
   Posted 1/26/2009 8:37 PM (GMT -7)   
I think it kills sex drive, although I hear many do and I gained weight on it.  Other then that... well what more can I say?  If those aren't issues for you it's helped my anxiety tremendously and I believe my pain is much better. :)

Fibromyalgia (DX'd Dec 07) ~ Generlized Anxiety ~ Migraines ~ IBS ~ Asthma ~ Allergies
Cymbalta   Topamax   Claritin   Tylenol   Ibuprophen

New Member

Date Joined Jan 2009
Total Posts : 8
   Posted 1/26/2009 8:54 PM (GMT -7)   
I was going to try Cymbalta, but I'm on Lyrica and Prozac and I have to watch my "liver" because I have a liver disease as well as Fibromyalgia and if you have a liver disease they recommend that you do not take Cymbalta...  Everyone is different and medications effect people differently I think..   Good luck with your decision though...   Hope it works for you blush

Veteran Member

Date Joined Apr 2008
Total Posts : 1522
   Posted 1/26/2009 10:52 PM (GMT -7)   
My mom had a weird side effect "reckless spending". She's on disability with a very limited income. She charged over $6000.00 in a few months time and had nothing to show for it. She had been on it for a few years and her doc had recently increased her dosage. She then had a terrible time stopping the Cymbalta. If we had been aware of this possible problem, we might have noticed something before she went into such deep debt.

stitching star
Regular Member

Date Joined Oct 2008
Total Posts : 38
   Posted 1/27/2009 3:51 AM (GMT -7)   
I wish you luck with it. I would do a google search on "cymbalta withdrawal" and on "cymbalta side effects" to see what you may be getting into. I had absolutely no reaction of any kind to it. No help with depression or with pain, no side effects and no withdrawal.

As with most meds of this kind, you will probably need to be on them for several weeks, up to 6 weeks, to see the full effects of the meds. If you DO have any side effects, or any suicidal or homicidal thoughts, PLEASE PLEASE PLEASE call your doctor!! This is one of those medicines that can give you that during the first few months of treatment.
SAHM, kids are the light of my life
dh of 17 yrs, my sweetie
ds 16yo, great kid, Sr. in high school
dd 13yo, my reward, homeschooled
ds 8yo, amazing kid, great magician
2 furbabies - Gracie and Capn Morgan, both cats
1 featherbaby - cockatiel - Goldi the Evil
I have always imagined paradise will be some type of library.
     -Jorges Luis Borges

Regular Member

Date Joined Jan 2009
Total Posts : 33
   Posted 1/27/2009 12:34 PM (GMT -7)   
I have been taking cymbalta for about 2 or3 months now, and it was done wonders for me. I still experience daily pain but it helps me emotionally deal with it better. It also helps me to think clearer(in less of a fog) The trick Ive found to make it work best for me is to take it first thing in the morning when i wake up. LIke the MINUTE i wake up. Im not sure why it makes it work better but it does. I also started on the 30mg which worked a little but then when i got onto the 60 it worked even better. It can take 3 or 4 weeks to really start seeing it helping in some people. And My sister in law and mother in law also take it and it works well for them. I always have bad bad bad side effects on medicine but for some reason didnt with cymbalta. Everyone reacts differently though.
Fibromyalgia, CFS, Gastroparesis, IBS, tarsal tunnel in both feet, scoliosis, orthostatic intolerance, anxiety & depression. CYMBALTA, ULTRAM, SOMA, PROBIOTIC FORMULA W/ACIDOPHILLUS, MIRALAX, FIBER CHOICE, MULTI-VITAMIN, SUPER B-COMPLEX, MAGNESIUM MALATE.

New Member

Date Joined Jan 2009
Total Posts : 19
   Posted 1/27/2009 7:36 PM (GMT -7)   
I also have a med phobia. I am comfortable with my hydrocodone (vicodin 7.5) that I tale 2x per day never any more than that. I did try a lot of different meds, one was cymbalta, and I did not like it at all. In addition to the horrible dry mouth(felt like sand in my mouth) it just made me feel strange. I now have been given Lyrica, and it still is sitting unopened on the shelf.

A new medication was just approved last week and it will be coming out in march, I think its called Savelle, or something like that, but the side effects dont look to bad.

Regular Member

Date Joined May 2008
Total Posts : 59
   Posted 1/29/2009 10:32 AM (GMT -7)   
Thanks for all the responses. I appreciate the information.

Well, I did take one of the Cymbalta pills and it made me sick to my stomach. I took it with food, as my doctor recommended, but it still made me too sick.

I think I will pass on this medicine, maybe I will try another that does not have so many side effects.

I see from some of your signatures that some of you are taking Ultram (or Tramadol) and Cymbalta (or another anti-depressant). Did your doctor worry about Serotonin Syndrome (and real bad reaction to Tramadol and SSRI's)?
I am just curious, because there is a warning on Cymbalta & Ultram not to take them together.

I went off my Ultram for 2 days so I could try the Cymbalta, BIG mistake. I was in too much pain without it.

I am going to stick with my Lyrica/Ultram combo for right now I guess.

<FONT]Lyrica 150mg (3X a day), Ambien 10mg, Darvocet N-100, Aspirin 325mg (as needed for headaches), still in pain.

New Member

Date Joined Jan 2009
Total Posts : 3
   Posted 1/30/2009 1:31 AM (GMT -7)   

I have been following this forum for quite some time now, but this is my first post, so please be patient with me!

I started taking Lexapro at first, but it really made me feel like a zombie, even though it relieved my depression. In July, my neurologist changed the Lexapro to Cymbalta, hoping that it would help with my headaches and the pain from the fibro. It did quite a good job. I had less pain in my chest and hips, and the headaches were really eased. Unfortunately for me, in October, I was in a car wreck and hit my head again. And since then, the Cymbalta stopped working as well. I was only taking 30mg a day.

When I first started taking it, I took 30 mg for a week, then I raised it to 60mg. At 60mg, my headaches worsened, so I cut back to taking 30mg twice a day. I had a little nausea after first, but nothing too bad, and now I have none at all.

I am now also taking Neurontin, and that has really eased my migraines.

Good luck to you.

Hyperprolactinemia, low thyroid, aHGH, costochondritis, fibromyalgia, depression, post concussion syndrome

Dostinex, levoxyl, genotropin, mobic, Cymbalta, Neurontin

Regular Member

Date Joined May 2008
Total Posts : 59
   Posted 2/2/2009 4:55 PM (GMT -7)   
Does anyone have any information on Serotonin syndrome?
Lyrica 150mg (3X a day), Ambien 10mg, Darvocet N-100 (as needed), Aspirin 325mg (as needed for headaches), still in pain.

New Topic Post Reply Printable Version
Forum Information
Currently it is Friday, November 24, 2017 6:27 AM (GMT -7)
There are a total of 2,897,389 posts in 318,010 threads.
View Active Threads

Who's Online
This forum has 157580 registered members. Please welcome our newest member, Beth Louise.
253 Guest(s), 4 Registered Member(s) are currently online.  Details
Doggiedo, Benoît, Uniform Charlie, straydog

About Us | Advertise | Donate
Newsletter | Privacy Policy & Disclaimer
Follow on Facebook Follow on Twitter Follow on Pinterest
©1996-2017 LLC  All Rights Reserved.