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New Member

Date Joined Aug 2008
Total Posts : 16
   Posted 6/30/2009 3:11 PM (GMT -7)   
Hi all!
My new Dr. just gave me a sample pack of Savella. She said it's the newest drug approved for Fibro. Anyone know anything about it? Used it?

Regular Member

Date Joined May 2006
Total Posts : 44
   Posted 7/1/2009 8:19 AM (GMT -7)   
My Dr. also gave me a sample supplyof Savellla.  I had read about it on an earlier post.
I went to the pharmasist and he wasn't familiar with it.  It pull up some info for me and I was not willing to take the medication.  During the trial study a large number of participants and extreme side effects .  Also very bad for people with hyp0ertention. 
Ask your pharmacist for info before taking.
Other member had severe side effeccts.  extreme dizziness, vomitng, diareahha and other harsh side effects

Veteran Member

Date Joined Jan 2005
Total Posts : 9090
   Posted 7/1/2009 9:15 AM (GMT -7)   
Hi and thanks for bringing this new medicine to the forefront! I did some research and found some fairly good reading on it. This new med was released for fibro in March so my opinion is...the jury is still out except for trials that were done for the FDA but it seems we're getting opinions already. This is in the antidepressant class of medications and does carry the "black box" warning that is required but...some people have found it easy to take with good results. Not sure how long the good results last though. Some who try Lyrica or Cymbalta feel great for several months and then it wears off. Will be interesting to see.

Here are some links to good information..IMHO

this one has links to trials and articles..

very technical stuff...

Hope this helps someone...
Co-Moderator Fibromyalgia & Chronic Pain Forums ~~~
Fibromyalgia, Ulcerative Colitis, Insulin dependent diabetic, PTSD, dermatitis herpetiformus, osteoarthritis, collapsed disk, and a few other side dishes.


If you ask what is the single most important key to longevity, I would have to say it is avoiding worry, stress and tension. And if you didn't ask me, I'd still have to say it.
George Burns

New Member

Date Joined Aug 2008
Total Posts : 16
   Posted 7/1/2009 6:02 PM (GMT -7)   
Thanks for the replies. I am going to give it a try. It is a gradual start up which I hope will minimize any side effects. I have a two week sample so I'll let you know how it goes. This is only day two. She said in addition to supressing the pain it is supposed to help with the insomnia and anxiety/stress. All of which I think is a big plus. No hypertension here so that may be why she suggested the trial.

New Member

Date Joined Jul 2009
Total Posts : 3
   Posted 7/1/2009 8:31 PM (GMT -7)   
I just started this med last night. Although, I couldn't find any info within the packet regarding drowsiness as a side effect, I ended up sleep most of the day. So just a heads up, you may want to start it on a weekend or non-working days.

lost in philly
Regular Member

Date Joined Jan 2009
Total Posts : 243
   Posted 7/2/2009 7:17 AM (GMT -7)   
Hi all, I have been on Savella for over 2 months. I would highly suggest that you consider talking with your Doc and cutting the pills in half at first--so that the titration packet you are talking about will actually take 4 weeks, instead of 2 to work up to the 50mg dose.
For me, having fibro and being very sensitive to medications...this med was VERY hard to take the first 3 weeks. Lots of stomach upset! But I have toughed through it and it is much better. I am still sick to my stomach sometimes after I take it, but not like the dizziness and vomitting in the first 3 weeks.
I have not noticed any change in my pain level (my pain is pretty high as I am still a somewhat newly Dx). But I have noticed a huge improvement in my cognitive abilities--much more alert during the day!
I dont know how long I will stay on it, but for now the benefits outweigh even the horrible first 3 weeks...that and all the welcome weight loss! Finally a pill that doesnt make you gain weight! lol

Good luck & go slow with this drug!
lost in philly

Fibromyalgia, Endometriosis, Migraines, Asthma, Chronic Fatigue

Savella, Topamax, Morphine, Percocet, Wellbutrin, Abilify, Crestor, Resoril, Loestrin, Imitrex

B12, Magnesium, Melatonin, Omega3

"Knowing without doing is like plowing without sowing."

New Member

Date Joined Jul 2009
Total Posts : 1
   Posted 7/13/2009 5:13 PM (GMT -7)   

I just wanted to reply to the questions about savella.  First of all I have had Fibromyalgia since my mid-twenties. Along with all-over muscle aches, I have severe migraines, brain fog/forgetfulness, IBS, extreme fatigue, muscel fatigue, feelings of being bruised all over my skin, vertigo and unexplained dizziness and lastly depression due to constant pain. I have been on cymbalta, topamax, lyrica, and many many other medications to try to control the pain and fatigue. In the past three years I have I've nearly went crazy with all the meds tried. I was told I have a low threshold for medications which was the reason why the side effects of any med was so severe. So after almost burning down my house due to my forgetfulness I  finally gave up on all fibro meds and was just dealing pain and taking my meds for the migraines and IBS.  It was a difficult path I chose and the constant pain took a toll on me.  So, once again my doctor discussed taking medication and assured me that he would monitor me weekly if I chose to take it.  The medication was Savella and after many talks with my husband we finally decided that I'd try medication one more time.  It's been three months now and Savella gave me my life back. It is a slow dose uptake.  The only side effects I encountered were slight constipation which was delt with by changing my diet slightly, I was a little more emotional then normal for the first month but it went away after about 5 weeks, and I feel full about a half an hour after I take it for about an hour ( I still feel that way ).  I take it twice, once in the morning and once at night with 50 mg of tramodol with each dose.  I still have painful days and weeks but not constant, usually at the end of the day and way less severe.  My fagtigue only gets the best out of me once a week which results in a three hour nap.  I'm alert and happy and feel like I can take on anything.  Like I said, I do still have some bad days but my bad days now are like my good days were when I wasn't on any meds.  The best thing is I haven't had any IBS and very few migraines since I started Savella.  When I do get a migraine the migraine med works and I'm not debilitated all day long like I use to be.  There is no next day migraine hangover which is incredible. Savella has changed my life and I look forward to telling others about it.  I will still need to get the test for vitamin D deficiency as does anyone with Fibromyalgia.  To many links to Vitamin D deficiency and Fibromyalgia are in the litature to ignore that posibility.  Hope this helps someone out there.

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