I have tried both of these medications before. While everyone is different, I found that the side effects to both of them were definitely worse than their benefits. Lyrica made me very groggy and I felt like I was in an extreme fog all of the time. I would get easily cofused and forget things all the time. I would feel like there were periods of time that would just go completely blank in my mind. It scared me. Plus, I never got any pain relief from Lyrica.
As for Cymbalta, it did help with my depression. I take Celexa normally, and I do think the Cymbalta helped a little bit more, but as far as pain relief goes, it didn't seem to make any difference. Plus, it made me tired, sick to my stomach, messed with my vision, and made me sweat like crazy all the time and get cold chills.
Over all, I think that both of these medications are extremely expensive and neither offered me enough relief to be worth it. Of course, everyone is different and you may find it beneficial to try them. Most doctors have samples they can give you so you can try the medication without paying for it. If you don't want to try it, you may want to ask your doctor about something like amytriptiline (a tri-cyclic antidepressant). I've been taking it for two months and it helps a lot with my stiffness and a little with the pain. It does make me a little drowsy, but I take it before bed and it also helps me sleep. It's a generic and isn't very expensive at all. Keep in mind that there are many medications other than just lyrica and cymbalta that may help you. The best thing you can do is talk to your doctor about trying some different things and see what works best for you.
Fibromyalgia, Depression, Anxiety
Amytriptiline, Flexeril (PRN), Percocet (PRN), Ambien (PRN at bedtime), B12
Be not afraid of going s l o w l y, be afraid only of standing still.