fibro and malic acid double blind study and other stuff

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Date Joined Jul 2008
Total Posts : 1495
   Posted 5/30/2010 10:46 PM (GMT -7)   
This is part of the abstract of an article I found in pub med.  They tested low dose malic acid on short term and high dose malic acid longer term against placebo and found that the high dose and longer treatment resulted in significant decrease in pain and tenderness.
RESULTS: No clear treatment effect attributable to Super Malic was seen in the blinded, fixed low dose trial. With dose escalation and a longer duration of treatment in the open label trial, significant reductions in the severity of all 3 primary pain/tenderness measures were obtained without limiting risks. CONCLUSIONS: These data suggest that Super Malic is safe and may be beneficial in the treatment of patients with FM. Future placebo-controlled studies should utilize up to 6 tablets of Super Malic bid and continue therapy for at least 2 months.
I looked this up because someone said I should try Valerin, a mostly valerian root herbal supplement.  When searching for Valerian and fibromyalgia I found that plain water whirlpool baths help decrease pain levels while whirlpool baths with pine oil will improve sleep and well being.
There is also a new norepinephrine and serotonin reuptake inhibitor that helps.  One of the recent theories is polymorphism of genes that have something to do with serotonin and norepinephrine and chaticholomine (sp?).
And that's all I have to say about that.

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Date Joined Apr 2005
Total Posts : 17557
   Posted 5/31/2010 7:59 AM (GMT -7)   
In the double blind studies I saw using malic acid and magnesium,   you had to be taking at least 2,400 mg of malic acid to get relief.  Lower doses did nothing.  I talk about this in the Fibro 101 thread.  I have been using this for several years and have done well with it.  It doesn't work with everyone but it's worth a try.  Better than narcotics!
Here is a link that explains this far better than I can.

Forum Moderator/ Fibromyalgia
Fibromyalgia, Crohn's Disease, Ostomy, Diabetes, Autoimmune Inner Ear Disease, Osteoporosis
God does not give us a spirit of fear, but of power and of love and of a sound mind.    2 Timothy 1:7

Post Edited (Sherrine) : 5/31/2010 9:23:24 AM (GMT-6)

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