Starting Lyrica today...

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Regular Member

Date Joined Apr 2006
Total Posts : 169
   Posted 6/3/2010 9:12 AM (GMT -7)   
Hi, this will be my first time trying Lyrica, Dr. asked if I wanted to try Cymbalta or Lyrica, Cymbalta, tried it a few years ago and had a very bad stomach next day, so was told to stop it.  Dr. told me to stop my Gabapentin, I was on very low dose and this made me fall asleep w/in 1/2 hour, but I would wake up about an hur later or so.
I asked him if Lyrica will cause weight gain, don't need it.   I gained 8lbs just this week, aagh!, the funny thing is I know I've been eating alot less, when I eat, after a few bites, I feel full and stop eating.  This feeling just started in May 2010. I'm glad I was eating less but to be weighed yesterday and have gained that much, I was surprized.
Dr. did say some people do gain or some lose weight, but I will have energy.
Just wanted to know what to expect when I start taking this new med.

Veteran Member

Date Joined Jun 2007
Total Posts : 906
   Posted 6/3/2010 9:28 AM (GMT -7)   
I did gain weight, about 30 pounds, which I did not need. Lyrica didn't help my pain or my energy, but it made so much difference in my sleep that I'm still taking it, over 2 years later. I don't know how bad my sleep would be without Lyrica, but it was almost non-existent before. Good Luck, Diane
Fibromyalgia since 1984, Sjogren's, Hashimoto's Thyroiditis, Auto-immune eczema, GERD, osteoarthritis, IBS, RLS, sleep apnea

Regular Member

Date Joined Jun 2009
Total Posts : 286
   Posted 6/3/2010 10:54 AM (GMT -7)   

I have been on Lyrica for almost a year and a half now. I was originally put on it for my trigeminal neuralgia. (Nerve pain in the side of the face.) I have not had too many problems with Lyrica, although I do know some people who have. My best advice would be to write down any changes you may notice, and then discuss them with your doctor. Also check out for common side effects.

Good luck!

"Anyone can give up, it’s the easiest thing in the world to do. But to hold it together when everyone else would understand if you fell apart, that’s true strength."


Dx: Fibromyalgia, CFS, Trigeminal Neuralgia, TMJ, Migraines, Anxiety, Insomnia, Acid Reflux, RLS, Asthma, Hypothyroidism.
Rx: Celebrex, Buspar, Savella, Lyrica, Neurontin, Requip, Nexium, Symbicort, Compazine, Lunesta, Synthoid.
Supplements: Vitamin B Complex, Vitamin D, Vitamin C, Iron, Malic Acid/Magnesium

Forum Moderator

Date Joined Nov 2008
Total Posts : 5948
   Posted 6/3/2010 11:49 AM (GMT -7)   
For me, it just stopped helping with the pain after a couple of months. So, I quit.
    Diagnosed: Fibromyalgia, possible Meniere's, elevated liver enzymes, skin grafting on back, arthritis, scoliosis, lumbar disc damage, sciatica, IBS, migraine headaches, tachycardia, skin cancer surgeries on face
    Meds: Nortriptyline, Clonazepam, Darvocet as needed
    Multivitamins, l-lysine, probiotics, magnesium, malic acid, calcium + vit. D, vit. C
    Chiropractic adjustments
Be yourself.  Everyone else is already taken.

Veteran Member

Date Joined Jan 2010
Total Posts : 1097
   Posted 6/3/2010 1:47 PM (GMT -7)   
I was on Lyrica for about 6 months and in that time, I gained about 40lbs, plus other side effects that made it impossible for me to stay on. I stopped taking it, and started Cymbalta. For the first 4 days, I was soooooo nauseated (which totally stressed me as I can't physically vomit anymore since having a Nissen Fundoplication for GERD), but on the 5th day, it was gone and I haven't had a single problem since.

The Cymbalta helps a lot with the Fibro pain and my doctor also has added in Cesamet for me so I'm getting pretty good pain relief now for the most part (aside from everything else I deal with).

Good luck with the Lyrica...I hope it really helps you!

Conditions: Fibromyalgia, Severe Myofascial Pain, Chronic Pelvic Pain (with permanent muscle damage), Femoralacetabular Impingement (CAM and Pincer), Reynauds, IBS, Surgical Adhesions, Ophthalmic Migraines, Severe Hot Flashes (both Surgical Menopause and medication related), plus physically unable to vomit due to the Nissen, and I have extremely tiny veins with a lot of scar tissue...a joy when it comes to having to give blood or get an IV started

Surgeries: Appendix, Uterus, Nissen Fundoplication for GERD, Left Ovary, Gallbladder, Right Ovary, TVT

Medications: Oxycontin, Cesamet, Tramacet, Cymbalta, Flexeril and Clonidine plus Laxaday, Vitamin D and a Multi-Vitamin daily

Regular Member

Date Joined May 2010
Total Posts : 25
   Posted 6/3/2010 4:58 PM (GMT -7)   
I tried Lyrica twice. Each time I had to quit within a week because I was allergic to it. I plan to ask my doctor about cymbalta. I am on antidepressants and have learned medical tests show they do help wiith the pain. I can atest to that from my personal experience. Turns out it has to do with serotonin levels.
Fibromyalgia from a bad car accident.
I was waiting for traffic and someone on a CELL PHONE hit my car at 65MPH and totalled it.
PTSD, Anxiety, Depression, Chronic Fatigue, Arthritis and other stuff sprinkled in for good measure.
Wanna Sew

confused Okie
Regular Member

Date Joined Apr 2009
Total Posts : 164
   Posted 6/3/2010 9:20 PM (GMT -7)   
Lyrica helped my pain, but it always came back and we upped the dose every couple months. I gained 30 lbs or so and when it stopped again I asked to back off and stop it. I will say, if anyone decides to go off of it you will probably need to do it gradually. My PCP told me just to stop, not good. I ended up tapering myself off with some of the lower doses I had and it took a while. It was pretty hard to get off of, I took it over a year. I had similar problems with Effexor and Paxil. I hope it works for you, you have to remember that we are all different and react to meds differently.
If you think you can, you can. If you think you can't, you won't.
I may not do things like other people, but I get things done in my own way, in my own time.

Regular Member

Date Joined Apr 2010
Total Posts : 372
   Posted 6/3/2010 9:38 PM (GMT -7)   
I have been taking it since January, and it does seem to help with pain. I have not gained weight. However, I've been dieting since that time, and I find it nearly impossible to lose weight. Not sure if this has anything to do with it.

Regular Member

Date Joined Oct 2008
Total Posts : 111
   Posted 6/5/2010 11:11 PM (GMT -7)   
I'm with you, Syl, I just started Lyrica about a week ago. My doctor had me stop taking Restoril and start taking 50mg of Lyrica at night. She told me if I felt fine I could take 100mg at night, and that we'd slowly build up the dose. I felt absolutely nothing at all with 50mg, so I starting taking 100mg. Wow, what a difference, and not for the better!

My doctor told me Lyrica would probably make me sleepy, but it doesn't really. I get sleepy right after I take it, but before I can fall asleep I start to get wired. Once I finally get to sleep, I feel spatially disoriented in the morning, like the world is moving and I can't quite focus on anything. My depth perception is shot and my motor skills and balance are slightly off. It's more amusing than anything else at this point, but if it doesn't go away soon I'll have to conclude that Lyrica is not for me. I need to be able to drive!

So that's me on Day 8. How are you doing now, Syl? Hopefully you're having a better time than me!
Dx'd with: fibromyalgia February 2008, dysthymia & dysnomia January 2009, biliary dyskinesia January 2010

I had a laproscopic cholecystectomy in January 2010.

Meds: Savella, Vitamin D, Lyrica

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