Best Pain medication

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New Member

Date Joined Jan 2011
Total Posts : 2
   Posted 1/16/2011 3:20 PM (GMT -7)   
I was recently diagnosed with Fibromyalgia this past year. My Dr put me on Celebrex and nortriptyline, with this combination I have enjoyed some success in reliving pain. My question is for everyone on the forum, what is the best pain medication for fibromyalgia that you have taken? I appreciate all the responses greatly!

Veteran Member

Date Joined May 2010
Total Posts : 1556
   Posted 1/16/2011 3:34 PM (GMT -7)   
Hi Sunny, I think you have just asked a very difficult question, we are all so different in what helps us and what doesn't, I cant take oral pain meds because they put me in more pain than I was in before I took them. I use a fentanyl patch for my pain, Prozac for my depression, and valium as a muscle relaxer but that is just what works for me. Others with fibro are totally different.
Gentle Hugs

PS welcome to our fibro family hope to hear from you soon.
DX: Fibro, Gerds, COPD, Osteoarthritis, Osteoporosis, High Blood Pressure, and Depression.
When I get where Im going dont cry for me down here. (Brad Paisley & Dolly Parton)

Forum Moderator

Date Joined Apr 2005
Total Posts : 17528
   Posted 1/16/2011 3:39 PM (GMT -7)   
Hi, Sunny!  Shirley is right.  What works for one doesn't necessarily work for another.  I use ibuprofen with food (that's an NSAID like Celebrex), extra strength Tylenol, malic acid/magnesium supplements and vitamin D3 supplements to help with pain and fatigue. 
Be sure to check out Fibro 101...the first thread on the forum.  There are links to good info about fibro and you will learn a lot there.  There are links about the supplements and vitamins that I mentioned above and how they work in your body.  It might be something to bounce off your doctor.
Don't hesitate to ask questions because we are here to help you.  I'm looking forward to getting to know you better.  Hope to hear more from you soon.
Forum Moderator/Fibromyalgia
God does not give us a spirit of fear, but of power and of love and of a sound mind. 2 Timothy 1:7

Regular Member

Date Joined Sep 2010
Total Posts : 235
   Posted 1/16/2011 5:26 PM (GMT -7)   
For me is the combination of Lyrica, Cymbalta, Mobic (new for me), Ambien, and Yaz. Took a lot of playing around with doses, what time of day to take them, etc. before I had the best pain relief I've had yet. It's really weird, most people have to take their cymbalta at night because it can make you sleepy. I have to take mine mid day because any other time, it made me sleep during the day and couldn't sleep at night. Now I am pretty good. Awake during the day and sleep fairly well at night. Good luck to you and my advice, don't "not" try something because you heard someone else had a bad reaction to it. We all are different. And if you try something and it doesn't work, try something else and keep trying until you find what works!!
Fibromyalgia, migraines, arthritis, PCOS, IBS, anxiety, chronic insomnia; Lyrica, ambien, yaz, cymbalta, lidocaine patches, midrin if needed, (fish oil, D3, Co-Q10, multi) PS: I think fibromyalgia is a jerk!

Love, hope, and hugs,

Regular Member

Date Joined Jul 2010
Total Posts : 463
   Posted 1/16/2011 6:19 PM (GMT -7)   
For me, amitriptyline and tramadol. Would use ibuprofen but have UC so not allowed... The key for pain relief for me is to sleep well, allowing everything to relax at night. If I don't sleep, life is hell the next day.

And, using a memory foam mattress (not-name brand).

Veteran Member

Date Joined Aug 2010
Total Posts : 795
   Posted 1/16/2011 6:22 PM (GMT -7)   
Hi, Sunny,

I agree with all the other replies. Everyone reacts differently to medication, and what works for one may not work for another.

I take Lexapro, Soma, and Tramdol to control my pain. It took me quite a little while to "get it right". I have to take the Tramadol on a regular basis every day or the pain gets out of hand. If I wait until I feel pain, it is too late. I suffer for two days.

Hope this helps!
Fibromyalgia, Inflammatory Arthritis, Osteoarthritis, Asthma, High BP, DDD, Bulging Discs in Cervical & Lumbar Spine, GERD, Prediabetic
Prednisone, Lexapro, Cardizem, Lisinopril, Advair, Lipitor, Vit D, Joint Supplements, Soma, Tramadol, Fish Oil Supplements
I take one day at a time, and try to save my energy for the joy in life.

Veteran Member

Date Joined Jul 2009
Total Posts : 4796
   Posted 1/16/2011 7:33 PM (GMT -7)   
Hi Sunny, welcome to the forum!

Yup, we're all unique and it is usually trial and error before you might find the right combo for you. I take Savella daily and use
Flexeril (cyclobenzapprine) a muscle relaxer when needed.

I believe our mindset is very important also in dealing with pain.
Doing what we can to distract pain is important...not letting pain be our focus...learning relaxation techniques...deep breathing and
meditation is helpful in easing pain....exercise too!

Hoping you will find what works for you!

hugs, Robin
Fibromyalgia, MCTD (Lupus, Scleroderma & RA)
Raynaud's, Degenerative Disc Disease, Osteoarthritis,
Osteoporosis, Hypertension and Migraines

A new day, a new beginning :)

Veteran Member

Date Joined Oct 2009
Total Posts : 4931
   Posted 1/16/2011 8:41 PM (GMT -7)   
Hi Sunny -
I've tried everything the others have and much more and reacted badly to everything except tramadol, diazepam and Ambien (sleep).

Flexeril helps with muscle relaxing but I can't take it with tramadol - get serotonin syndrome. My pain doc is afraid I'll get addicted to diazepam if I take even 1 a night.

Veteran Member

Date Joined Nov 2010
Total Posts : 877
   Posted 1/17/2011 8:31 AM (GMT -7)   
I take mobic for the meniscus tears, arthritis, bursitis. I take tramadol and flexeril for the fibro and I take ambien cr for a good nights sleep. If I keep up with these meds on a maintenance schedule everything usually stays down to a low roar. But sometimes something comes along and throws a stick in and .......extra aches and pains.

My iron levels dipped very low (don't know the reason why, yet) and this threw me into a very long flare. Now I am back to fair normal and I had to go off the mobic for an up coming surgery and now my knees are hurting.....I have just come to the conclusion that every day is a new day and I will deal with it the best I can with whatever means there are available to me at the time.

I hope that with time and trial you find what works for you. Don't be afraid to suggest different meds with your doctor and let them know exactly how they do or do not work for you.

Fibro, meniscus tears in both knees, arthritis in both knees, B-12 defficiency, pernicious anemia, vit. D defficiency, mild alergies, and insomnia. mass on thyroid - biopsied, beneign, but very large and still has to come out - January 25th.

Veteran Member

Date Joined May 2008
Total Posts : 704
   Posted 1/18/2011 2:16 PM (GMT -7)   
Hi Sunny!!
Yep, everyone of use has a different "script" if you will for relief. I'm pretty much taking what Shirley takes,
I use the fentanyl patch and oxy IR for break thru pain, I take prestique for depression, and ativan for anxiety and to help me sleep. I am taking something new too, of course I can't think of what it is right now, lol but I will be back to name it soon.
I think it really depends some people see to have very bad pain all the time and then flares from that, then others are in a less amount of pain daily, but seem to get bad flares??? IDK...fibro is such a tricky thing. Just know that everyone is different, and everyone reacts to certain pain medications differently.

New Member

Date Joined Jan 2011
Total Posts : 7
   Posted 1/20/2011 1:53 AM (GMT -7)   
Hello Sunny,

I can't speak for others but at the moment I take Effexor XR in the morning, Lyrica in the morning and afternoon and then Trazadone at night to ensure I get a good nights rest.

Hopefully in the near future we will be moving to Cymbalta instead of the Effexor for Depression or whatever the Doc things is wrong with my attitude!

Frankly, I think the biggest thing that has helped me is the Effexor and the Trazadone to date... my mind is clearer than it has ever been and when I wake up rested and in a good mood I can deal with whatever FMS throws and me and kick it's ***. (most of the time)

Diet is huge for me too, as is what I drink and what I do during the day. I am an avid runner and work out as much as I can. I figure if I'm going to be sore anyway I might as well be sore for a reason. It's not like aches and pains from weights or running are going to be anywhere near as bad at the FMS is.

My pain is fairly constant fairly bad imo. I seldom have flares which is a good thing because I experienced one and that knocked me on my butt.

Your best option is to talk to your Doctor and possibly a nutritionist and/or dietician and see what they all have to say. Most insurance companies have protocols and things you have to go through before you get to the good drugs, so it may take some time but rest assured your Doctor is going to do their best to help you in your situation. I've often found the worst thing to do is to go to your Doctor and ask for specific drugs as they, hopefully, know much more about them than we do!

Michael in Idaho

getting by
Forum Moderator

Date Joined Sep 2007
Total Posts : 41931
   Posted 1/20/2011 6:50 AM (GMT -7)   
I think if you ask for a specific drug, they often feel you are drug seeking, especially if it is a narcotic. So be careful with that. Mostly it is trial and error. They start you at the weakest thing and move up to find what works for you.

We are all different and different things help different people. So my advice is to try it and see what happens. If your meds aren't helping, let the doctor know and they will most likely try something else.

Just my two cents for what it is worth. Not much these

I do hope that you feel better soon.

Hugs, Karen
  Moderator-Depression and fibromyalgia
fibromyalgia, Chronic fatigue, depression,allergies
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