Lyrica was quite the buzz kill

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New Member

Date Joined Feb 2011
Total Posts : 18
   Posted 3/5/2011 6:31 PM (GMT -7)   
I have a few questions involving Lyrica for treatment of what we may think is Fibromyalgia. I have been in chronic pain for now almost 16 months now and the past few months it has been quite debilitating. I am only 18 year old healthy male, work out every other day now but was couch ridden every other week or so. I try to fight through the pain thinking working out will slowly help me get back into things but it appears no help. I do yoga, swimming, meditation, attuned diets, magnesium and fish oil supplements, the whole shibang.

I have tried Cymbalta (up to 120mg), lyrica, seroquel, etodolac, zanaflex, physical therapy, chiropractors, acupuncture, massages, and pinpoint injections and still no relief. I am at a 9 in my pain level and was recently given Lyrica to try to help.

I was told to start at 50mg for a few days and then go to 100mg. The first day I took 50mg and I felt amazing, my pain went from a 9 to around a 7 which being at such a terrible any relief seems amazing. I thought it would only get better. 2 days later I went up to 100mg and noticed not much more relief, I am now up to 150mg and back up to a pain level of 9. I was given quite alot of examples because my doctor has a good amount of trust in me. Today I tried 300mg desperate to see if dosage would fix anything but I went from about a 9 to an 8. I don't want to have to take up to 600mg a day for just partial relief and I dont know if Lyrica should get better with time.

Should I continue to try to take Lyrica or talk to my doctor about other methods? I probably will continue it as it does have potential to take minimal pain away but not enough. Any advice sounds great!

Forum Moderator

Date Joined Nov 2008
Total Posts : 5948
   Posted 3/5/2011 10:05 PM (GMT -7)   
Hi, zabumafu. Sorry to hear you're in so much pain.

All I can tell you is that Lyrica was a disappointment to me. It worked pretty well for a few weeks, and then - just stopped.

I sure wouldn't take more than the doctor prescribed - at least, not without getting an ok first. These drugs they give us for fibro can help some people, sometimes, but they are nothing to take lightly. Serotonin Syndrome, respiratory distress, liver or other organ damage - all kinds of really bad things can happen if you're not careful. It's not true that if a little is good, a lot is better! I would definitely talk to my doctor and see what s/he says.

Good luck! Debbie
...fibromyalgia, hashimoto's thyroiditis, hearing loss, elevated liver enzymes, skin grafting (back), arthritis, scoliosis, lumbar disc damage, sciatica, IBS, migraines, tachycardia, cancer surgeries (face).......daily Nortriptyline, Levothyroxine, & Clonopin, and Tramadol and Midrin as needed

New Member

Date Joined Mar 2011
Total Posts : 7
   Posted 3/5/2011 10:16 PM (GMT -7)   
Lyrica didn't help me. It caused brain fog, but did not dull the pain for more than a few days at the start. My dr just told me about savella. You might want to do some research on it. Sorry that you are hurting so.

Veteran Member

Date Joined May 2010
Total Posts : 1556
   Posted 3/6/2011 7:51 AM (GMT -7)   
Hi Zabumafu, welcome to our fibro family we have a great group of people here that are always willing to try and help.

As far as the Lyraca Im with Debbie, be very careful about raising the dosages, always make sure you talk to the dr. first. I have never used lyraca but I have heard from so many others here on the board and know that it works for some of us but not for others as do most of the medicines out there. You just have to find what is right for you and that can take alot of trial and error.

I use Fentanyl patches, valium and I am on anti-depressants to control mine. Others like Sherrine can control theirs with Ibuprofen and Tylenol. We are a mixed group here who all understand what it is like to live in pain. Feel free to ask questions, vent when you need too or offer support to others.

Gentle Hugs

When I get where Im going dont cry for me down here. (Brad Paisley & Dolly Parton)

getting by
Forum Moderator

Date Joined Sep 2007
Total Posts : 41830
   Posted 3/6/2011 11:53 AM (GMT -7)   
Hi there,

I would talk to the doctor about something different if 300mg didn't help your pain much. You need something that works. There are many different pain relievers. Being you are young, I doubt that they would give you any narcotic pain relievers, but we have members that get relief from tylenol or ibuprofin. Take a look at the thread called "fibro101". You might get some valuable information for you there. There is a thread on malic acid and magnesium. That has helped me.

I hope that you feel better soon.

Hugs, Karen
Moderator-Depression and fibromyalgia

fibromyalgia, Chronic fatigue, depression, allergies

New Member

Date Joined Feb 2011
Total Posts : 18
   Posted 3/6/2011 8:56 PM (GMT -7)   
Thank you all for your worries and concerns. I wasn't worried about the dramatic dosage increase as I have an abnormally high tolerance to medication, why I don't know. I noticed no more significant effects than that of the 100mg a day yet at 3x the dosage. My doctor already mentioned if I was to increase my dosage my next step would be 300mg (3x a day) then anywhere from 400-600mg (3x) if needed to increase after. I wasn't worried about this dosage as I knew I would eventually reach this dosage maybe even high if it is successful. The lack of relief now, is miserable. I am back to the same pain as before yet it seems more irritating because I enjoyed the edge off atleast some pain for a few days.

I wish I could treat this with the occasional advil or ibuprofin but it does nothing but make me feel like I just ingested nothing but some sugar pills. Im trying to avoid narcotics because I dont like the idea of potentially being able to be addicted to an unhealthy substance; therefore I have tried quite a variety of other pain relief methods. I take a multivitamin and mineral along with 500mg magnesium supplements and 900mg with a protein smoothie everymorning as a healthy combatment. I have even started yoga and meditation to manage pain and insomnia. I will say the more intense cardio workouts coupled with yoga provides natural pain relief for about 15 minutes and can sometimes exhaust you so much that youll pass out regardless.

Regular Member

Date Joined Jul 2010
Total Posts : 105
   Posted 3/6/2011 9:33 PM (GMT -7)   
So I am with some others who have not ben able to use the Lyricas, savellas, and cymbaltas, among many others! Savella for me made me evil that stuff was satan in a pill!!! Didnt even stay on it long enough to go up to full strgnth, when i hit 25 mg twice a day I became satan! Lyrica and cymbalta both failed for me also, so now I am on my origional antidepressant prozac which besides the weight gain at least helped me stay somewhat happy! Though it does nothing for pain!

As far as pain meds, I have also run the list of those as well. I have a pretty much standing prescription for percoset as needed. Motrin and those things ate my stomach up. I was given dilaudid in a pill form but it does not absorb well apparently through pills form. When the oain is unbearable I would get either IV or IM Dilaudid or Toradol which actually worked great!

I am now on 25 mcg/h Fentanyl patches which are a godsend for me and take pain that was consistantly at a 8 or 9 down to a 2 or 4 with only a few bad breakthroughs requiring percoset. I still wished they would allow us to take our own torodaol shots cause for me that stuf was great and non narcotic, although it was very short acting. I also have valium for when my muscles act up.

My kitchen cabinet has pretty much any med for any thing from pain, to vertigo, lots of pukey pills, hormones, you name it i got it. I hope they can find a happy solution to at least dull the pain, that is what I am learning is the best I can hope for. Gets tough on days like today where i couldnt get the strewngth to turn my gas cap, and I wanted to throw in the towel , but know were here for you..... even if i dont post much cause usually forget what the original topic was about! :)

gentle hugs~

Fibromyalgia, Hysterectomy, CFS, Positive ANA test (unknown what autoimmune disease it is), Severe Carpal Tunnel,PCOS,Hip replacement
meds: Benicar, effexor, percoset, zofran, amitryptaline, premarin, multivitamins, valium

New Member

Date Joined Feb 2011
Total Posts : 18
   Posted 3/13/2011 2:43 PM (GMT -7)   
Reporting back now having taken 200mg daily for almost 2 weeks. I have also coupled this with physical therapy 3x weekly, yoga, and have had to take 2 aleve's daily. Pain is still at a 9 however I have been couch ridden all week and while on the heating pad after yoga and stretching I can get it down to a 7...but once I have to sit up and move around it peaks back up.

I have an appt on Tuesday with my back specialist and still waiting on a response from the xrays from my rheumatologist. I have physical therapy only 2x this week as I had to cancel one because I have my 5th interview with Apple tomorrow! Hopefully the last also. I'm kinda worried about being drug tested as the medication I take can cause false positives quite often for substances such as amphetamines, LSD, THC, opiates, and even cocaine! Who would have known that amoxicillin can cause cocaine false positives. Of course I don't use it but hopefully I just dont even have to be tested and explain my medications.

Any other ideas on pain therapy/things to discuss with my doctor on my next visit? I need to fix this before I go off to college in a few months.
Chronic Pain patient with unknown causes thought to maybe be Fibromyalgia.

Current (unsuccessful) medication: Lyrica, Etodolac, Zyrtec, Magnesium,Ambien, Lunesta, vitB complex, Omega 3, Multivitamin and Minerals.

Previous meds: Cymalta, Lyrica, Seroquel
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